Evidence map›Paper›PMID 40817620›Full record

ArticleJournal of clinical apheresis2025

Hematopoietic Stem Cell Donors' Experiences of Information and Side-Effects During the First Year After Donation-A Swedish National Study.

Annika M Kisch, Jeanette Winterling, Hans Hägglund, Gunnar Larfors, Stig Lenhoff, Simon Pahnke

Abstract read
In one paragraph

Article in Journal of clinical apheresis, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Annika M KischDepartment of Haematology, Oncology and Radiation Physics, Skåne University Hospital, Lund, Sweden.ORCID https://orcid.org/0000-0002-1536-3926
Jeanette WinterlingDepartment of Neurobiology, Care Sciences and Society, Karolinska Institutet, Stockholm, Sweden.ORCID https://orcid.org/0000-0003-4165-9015
Hans HägglundDepartment of Medical Sciences, Unit of Haematology, Uppsala University, Uppsala, Sweden.ORCID https://orcid.org/0000-0002-4382-4945
Gunnar LarforsDepartment of Medical Sciences, Unit of Haematology, Uppsala University, Uppsala, Sweden.ORCID https://orcid.org/0000-0002-1549-8695
Stig LenhoffDepartment of Haematology, Oncology and Radiation Physics, Skåne University Hospital, Lund, Sweden.ORCID https://orcid.org/0000-0003-1096-8915
Simon PahnkeDepartment of Immunology, Genetics and Pathology, Cancer Precision Medicine, Uppsala University, Sweden.ORCID https://orcid.org/0000-0002-3541-2027

Funding

Lions Cancer research in UppsalaThe Foundation of the Oncology clinic research in UppsalaThe Swedish Blood cancer SocietyThe Swedish Cancer Society (in Swedish: Cancerfonden)
6 · The paper itself

Abstract

The aim was to describe hematopoietic stem cell (HSC) donors' experiences focusing on information and side effects during the first year after donation. Our prospective Swedish cohort study with adult HSC donors was performed from 2019 to 2022, with questionnaires at four time points from before until 12 months after donation. 173 unrelated and 68 related donors participated, and the majority donated peripheral blood stem cells. All but one rated their donation experience as good or very good. At least one side effect was reported by 83% of participants. Six donors (2.5%) experienced either numerous side effects, at least one severe side effect, or prolonged side effects. Satisfaction with information was lower among donors having severe side effects and bone marrow donors. Overall satisfaction with the donation was lower among donors having severe side effects and unrelated donors. Donors were generally satisfied with the pre-donation information. Most experienced side effects that resolved within 2 weeks, which strengthens the case for unchanged donor follow-up 1 month after donation, with individualized follow-up for donors with persistent symptoms. Enhanced information regarding the risk of more severe or prolonged side effects appears warranted, and its effect on donor satisfaction should be evaluated.

Indexed as

Blood DonorsHematopoietic Stem CellsTissue DonorsAdultFemaleHematopoietic Stem Cell TransplantationHumansMaleMiddle AgedPersonal SatisfactionProspective StudiesSurveys and QuestionnairesSwedenexperienceshematopoietic stem cell donorsinformationside‐effectsstem cell donation

Identifiers

PMID40817620
PMCPMC12357066

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.