Evidence map›Paper›PMID 40817378›Full record

ArticleScientific reports2025

The critical dimension of memory engrams and an optimal number of senses.

Wendy Otieno, Ivan Y Tyukin, Nikolay Brilliantov

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

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0 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

3 authors.

Wendy OtienoDepartment of Physics, Loughborough University, Loughborough, LE11 3TU, UK.
Ivan Y TyukinKing's College London, London, WC2R 2LS, UK. ivan.tyukin@kcl.ac.uk.
Nikolay BrilliantovSkolkovo Institute of Science and Technology, Bol'shoi Bulvar 30, Moscow, 121205, Russia.

Funding

UK Research and Innovation EP/V025295/2
6 · The paper itself

Abstract

In this work, we analyse the fundamental question: how many senses are optimal for memory and learning. To answer this question, we introduce and analyse a novel kinetic model of memory engrams. The model, built on basic general principles and phenomenology, captures the engrams' emergence and evolution driven by their interaction with external environment, learning, and forgetting. We derive the corresponding kinetic equation governing the dynamics and evolution of engrams over time. We then solve this equation analytically and numerically through Monte Carlo simulations. We observe the formation of a steady state with a steady number of different engrams covering a fraction of the conceptual space. We analyze the impact of the dimension of the conceptual space on the steady state and discover the existence of a critical dimension, at which the number of different engrams is maximal; we provide a theoretical explanation of this observation. If each feature is associated with a different sense, the critical dimension corresponds to an optimal number of senses for a system aiming at keeping the maximal number of different concepts in its memory. We also reveal an apparent tension between the system's receptivity to new stimuli and concept sharpness-the higher the receptivity, the less sharp the learned concept becomes.

Identifiers

PMID40817378
PMCPMC12356968

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.