Evidence map›Paper›PMID 40817361›Full record

Observational studyJournal of general internal medicine2025

Virtual Reality as RESPITE: Relief Exploration for Sickle Pain Through Interventions Using Technology Engagement: A Hospital-Based Observational Study.

Nitin Vidyasagar, May Nguyen, Andrea Bundy, Nabil Abou Baker, Dima Kenj Halabi, Vineet M Arora, David O Meltzer, Valerie G Press

Abstract readObservational Study
In one paragraph

Observational study in Journal of general internal medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Nitin VidyasagarPritzker School of Medicine, The University of Chicago, Chicago, USA.
May NguyenDepartment of Medicine, University of Chicago, Chicago, USA.
Andrea BundyCenter for Transformative Care, University of Chicago Medicine, Chicago, USA.
Nabil Abou BakerDepartment of Medicine, University of Chicago, Chicago, USA.
Dima Kenj HalabiPritzker School of Medicine, The University of Chicago, Chicago, USA.
Vineet M AroraDepartment of Medicine, University of Chicago, Chicago, USA.
David O MeltzerDepartment of Medicine, University of Chicago, Chicago, USA.
Valerie G PressDepartment of Medicine, University of Chicago, Chicago, USA. vpress@bsd.uchicago.edu.ORCID 0000-0001-9961-4878

Funding

SMART POR: Supporting and Mentoring Across Respiratory Topics in Patient Oriented ResearchK24HL163408 · NHLBI · UNIVERSITY OF CHICAGO · PI Valerie G Press · 2023 to 2026
$485k
NHLBI NIH HHS K24 HL163408NIH HHS 1K24HL163408-01A1
6 · The paper itself

Abstract

backgroundThe opioid epidemic, side effects from acute and chronic opioid use, and low utilization of preventive medications for sickle cell disease (SCD) necessitate the development of novel strategies to manage painful vaso-occlusive episodes. Virtual reality (VR) has shown promise for pediatric patients with SCD; however, interest in VR among adults with SCD is under examined. Ensuring equitable access to VR-based interventions requires understanding of factors that determine patients' interest in VR.

objectiveTo assess interest, preferences, and predictors regarding interest in VR-based interventions to manage SCD-related pain.

designCross-sectional, observational, single-site study conducted between 2023 and 2024.

participantsHospitalized, English-speaking, had a SCD diagnosis, and aged ≥ 18 years. MAIN MEASURES: The primary outcome was participants' interest in using VR. General health literacy (HL) and electronic health literacy (eHL) were assessed using Brief Health Literacy Screen and eHealth Literacy Scale, respectively, to compare differences between participants interested versus uninterested in using VR to manage pain. Participants also indicated preferred gaming genres and barriers to VR use. KEY

resultsAmong 40 participants (80% response rate), most self-identified as Black (95%) and male (58%); 43% had low HL; and 13% had low eHL. Most (85%) participants indicated interest in using VR for pain management (n = 34/40). Participants uninterested in using VR were more likely to have low HL (100% vs. 33%; p = 0.002) and low eHL (67% vs. 3%; p < 0.001) than participants interested in VR. Skill development (82%; e.g., learning how to rock-climb) and adventure (82%) genres were most preferred among interested participants. Cost (65%) and access to VR devices (35%) were cited as notable barriers.

conclusionsThe present study identifies that people with SCD regard VR as a promising intervention for pain management. Future studies include designing equitably accessible VR interventions and assessing efficacy, paying attention to factors like electronic and general health literacy.

Indexed as

Anemia, Sickle CellPain ManagementVirtual RealityAdolescentAdultCross-Sectional StudiesFemaleHealth LiteracyHumansMaleMiddle AgedYoung Adultelectronic health literacyhealth literacypainsickle cellvirtual reality

Identifiers

PMID40817361
PMCPMC12612338

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.