Evidence map›Paper›PMID 40817215›Full record

ArticleItalian journal of pediatrics2025

Changes in lung function in children after pneumonia: a multicenter study.

Hejun Jiang, Jingsheng Dai, Guifang Zhou, Guijun Yang, Liwen Zhang, Shuhua Yuan, Jing Zhang, Jiande Chen, Mingyu Tang, Jilei Lin and 3 more

Abstract readMulticenter Study
In one paragraph

Article in Italian journal of pediatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Trial
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Hejun Jiang *Department of Respiratory Medicine, Shanghai Children's Medical Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Jingsheng Dai *Department of Pediatric, Shanghai Pudong New Area People's Hospital, Shanghai, China.
Guifang Zhou *Department of Respiratory Medicine, Linyi Branch of Shanghai Children's Medical Center, Linyi Maternal and Child Healthcare Hospital, Linyi City, Shandong Province, China.
Guijun YangDepartment of Respiratory Medicine, Shanghai Children's Medical Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Liwen ZhangDepartment of Respiratory Medicine, Shanghai Children's Medical Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Shuhua YuanDepartment of Respiratory Medicine, Shanghai Children's Medical Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Jing ZhangDepartment of Respiratory Medicine, Shanghai Children's Medical Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Jiande ChenDepartment of Respiratory Medicine, Shanghai Children's Medical Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Mingyu TangDepartment of Respiratory Medicine, Shanghai Children's Medical Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Jilei LinDepartment of Respiratory Medicine, Shanghai Children's Medical Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Li LiDepartment of Pediatric, School of Medicine, Putuo People's Hospital, Tongji University, Shanghai, China. baby_camel@163.com.
Yufen WuShanghai Children's Medical Center Outpatient and Emergency Office, Shanghai Jiao Tong University School of Medicine, Shanghai, China. wuyufen2007@yeah.net.
Yong YinDepartment of Respiratory Medicine, Shanghai Children's Medical Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China. yinyong9999@163.com.

Funding

Medical and Industrial Intersection Project of Shanghai Jiaotong University YG2024ZD20Shanghai Municipal Health Commission Healthcare Industry Clinical Research Special Project 20224Y0180Shanghai Municipal Science and Technology Commission 'Yangfan Plan' 23YF1425100Shanghai Pudong New Area Science and Technology Development Fund Livelihood Research Special Fund Healthcare Project PKJ2023-Y49Shanghai Pudong New Area Science and Technology Development Fund Livelihood Research Special Fund Healthcare Project PKJ2023-Y50
6 · The paper itself

Abstract

backgroundThere are few studies on the changes in lung function after pneumonia in children. This study aims to explore the changes in lung function in children after pneumonia and analyze the risk factors for airway disorder, especially the impact of different pathogen infection on lung function.

methodsThis study collected data from patients who were hospitalized due to pneumonia in ten Chinese hospitals between January 2023 and December 2024. Pulmonary function tests were performed to assess changes in lung function one week and one month after discharge.

resultsA total of 566 children were included in this study, with 40.6% of patients still showing airway disorder one week after discharge. Different pathogenic infections had varying effects on pulmonary function. MP (Mycoplasma pneumoniae) infection [OR (95%CI): 1.881(1.268-2.789), P = 0.001] and RhV (rhinovirus) infection [OR (95%CI): 2.402(1.027-5.621), P = 0.043] were significant risk factors for the occurrence of SAD (Small Airway Disorder) one week after discharge. Male gender [OR (95%CI): 2.219, P = 0.001] and MP infection [OR (95%CI): 1.681(1.024-2.761), P = 0.039] were significant risk factors for the occurrence of LAD (Large Airway Disorder) one week after discharge. No positive pathogen results [OR (95%CI): 0.366(0.168-0.800), P = 0.011] were significant protective factors for the persistence of SAD one month after discharge, while RhV infection [OR (95%CI): 7.286(0.802, 66.238), P = 0.077] and lung consolidation [OR (95%CI): 1.753(0.956, 3.214), P = 0.069] showed mild significance for the persistence of SAD one month after discharge. Male gender [OR (95%CI): 2.246(1.137-4.436), P = 0.019] and RhV infection [OR (95%CI): 1.967(1.630-237.549), P = 0.019] were significant risk factors for the persistence of LAD one month after discharge, while no positive pathogen results [OR (95%CI): 0.249(0.092-0.678), P = 0.006] were a significant protective factor.

conclusionsApproximately 40.6% of children after pneumonia still had airway disorder one week after discharge, which was closely related to different pathogenic infections. Patients with RhV pneumonia, in particular, should be closely monitored for changes in lung function after discharge.

Indexed as

LungPneumoniaChildChild, PreschoolChinaFemaleHumansInfantMaleRespiratory Function TestsRetrospective StudiesRisk FactorsLarge airway disorderLung functionPneumoniaRhinovirusSmall airway disorder

Identifiers

PMID40817215
PMCPMC12355759

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.