Evidence map›Paper›PMID 40817071›Full record

ArticleAntimicrobial resistance and infection control2025

Hidden transmissions of Pseudomonas aeruginosa ST111 -the importance of continuous molecular surveillance.

Jasmin Kaur Jasuja, Eva-Maria Klupp, Martin Aepfelbacher, Knut Kurt William Kampe, Michael Fabian Nentwich, Stefan Kluge, Johannes Karl-Mark Knobloch

Abstract read
In one paragraph

Article in Antimicrobial resistance and infection control, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jasmin Kaur Jasuja *Department for Infection Prevention and Control, Institute for Microbiology, Virology and Hygiene, University Medical Center Hamburg-Eppendorf, Martinistraße 52, 20246, Hamburg, Germany. j.jasuja@uke.de.
Eva-Maria Klupp *Department for Infection Prevention and Control, Institute for Microbiology, Virology and Hygiene, University Medical Center Hamburg-Eppendorf, Martinistraße 52, 20246, Hamburg, Germany.
Martin AepfelbacherInstitute for Medical Microbiology, Virology and Hygiene, Institute for Microbiology, Virology and Hygiene, University Medical Center Hamburg-Eppendorf, Martinistraße 52, 20246, Hamburg, Germany.
Knut Kurt William KampeDepartment of Intensive Care, University Medical Center Hamburg-Eppendorf, Martinistraße 52, 20246, Hamburg, Germany.
Michael Fabian NentwichDepartment of Intensive Care, University Medical Center Hamburg-Eppendorf, Martinistraße 52, 20246, Hamburg, Germany.
Stefan KlugeDepartment of Intensive Care, University Medical Center Hamburg-Eppendorf, Martinistraße 52, 20246, Hamburg, Germany.
Johannes Karl-Mark KnoblochDepartment for Infection Prevention and Control, Institute for Microbiology, Virology and Hygiene, University Medical Center Hamburg-Eppendorf, Martinistraße 52, 20246, Hamburg, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundA series of transmission of Pseudomonas aeruginosa ST111 bla

methodsFirst, routine epidemiological data ruled out patient-to-patient transmission and two initial diagnoses were assessed as externally acquired. After the discovery of the highly related cluster by whole genome sequencing, a more detailed epidemiological analysis was carried out, including previous hospitalizations. An environmental investigation was initiated due to a possible connection of transmissions with an intensive care unit.

resultsBetween 2018 and 2023 16 clinical isolates of Pseudomonas aeruginosa ST111 bla

conclusionsThis finding highlights the ability of high-risk clone ST111 to persist in hospital environments and emphasizes the importance of integrating molecular surveillance with routine epidemiology to uncover hidden transmissions. In this case, the frequent detection of the ST111 high-risk clone led to targeted environmental sampling, uncovering a prolonged outbreak that had gone unnoticed by conventional surveillance. The clone was eliminated from the ward during a reconstruction project.

Indexed as

Cross InfectionPseudomonas aeruginosaPseudomonas Infectionsbeta-LactamasesGermanyHumansIntegronsIntensive Care UnitsMicrobial Sensitivity TestsMolecular EpidemiologyTertiary Care CentersWhole Genome Sequencingbeta-Lactamasesbla VIM−2High-risk cloneOutbreakPseudomonas aeruginosaST111Whole genome sequencing

Identifiers

PMID40817071
PMCPMC12357456

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.