Evidence map›Paper›PMID 40817041›Full record

ArticleBMC pulmonary medicine2025

The association between core number and complications in ultrasound-guided percutaneous lung core needle biopsy for subpleural primary lung cancer: a retrospective study.

Mengjun Shen, Hongwei Chen, Jixin Shu, Yang Cong, Yi Zhang, Huiming Zhu, Yin Wang

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In one paragraph

Article in BMC pulmonary medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

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0cells of the map it votes in
3citing papers in PubMed
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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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3 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Mengjun ShenDepartment of Ultrasonography, Shanghai Pulmonary Hospital, School of Medicine, Tongji University, Shanghai, 200433, China.
Hongwei ChenDepartment of Ultrasonography, Shanghai Pulmonary Hospital, School of Medicine, Tongji University, Shanghai, 200433, China.
Jixin ShuDepartment of Ultrasonography, Shanghai Pulmonary Hospital, School of Medicine, Tongji University, Shanghai, 200433, China.
Yang CongDepartment of Ultrasonography, Shanghai Pulmonary Hospital, School of Medicine, Tongji University, Shanghai, 200433, China.
Yi ZhangDepartment of Ultrasonography, Shanghai Pulmonary Hospital, School of Medicine, Tongji University, Shanghai, 200433, China.
Huiming ZhuDepartment of Ultrasonography, Shanghai Pulmonary Hospital, School of Medicine, Tongji University, Shanghai, 200433, China.
Yin WangDepartment of Ultrasonography, Shanghai Pulmonary Hospital, School of Medicine, Tongji University, Shanghai, 200433, China. lpbbl@aliyun.com.

Funding

National Natural Science Foundation of China 82272007the Shanghai Health Commission 2023 Shanghai Health Industry Clinical Research Special Project 202340246
6 · The paper itself

Abstract

backgroundWith advances in lung cancer management, there is a growing need for larger tissue samples to enable tumor genomic analysis and characterization.This study aims to determine whether the core number obtained during Ultrasound-guided percutaneous lung core needle biopsy(US-PLCNB) is associated with post-procedural complications.

methodsThis retrospective study enrolled consecutive patients who underwent US-PLCNB for subpleural primary lung cancer at Shanghai Pulmonary Hospital between July 2019 and September 2021. Patient data were extracted from medical records, including demographics, lesion size, and core number. Post-procedural complications, including hemoptysis, pneumothorax, intolerable pain, pleural reaction, hemothorax, and delayed hemopneumothorax, were documented. Multivariate logistic regression models were used to evaluate whether the core number was an independent predictor of complications following US-PLCNB.

resultsA total of 1,151 patients (mean age, 64.47 ± 10.58 [SD] years; 278 [24.15%] females and 873 [75.85%] males) were included. The median lesion size was 58 mm (IQR, 41-77 mm). Among the 1,151 patients, 417 (36.23%) were diagnosed with lung adenocarcinoma, and 322 (27.98%) with lung squamous cell carcinoma. Post-procedural complications occurred in 41 patients (3.56%), including: hemoptysis (26 cases, 2.26%), pneumothorax (7 cases, 0.61%), intolerable pain (3 cases, 0.26%), vasovagal reaction (2 cases, 0.17%), hemothorax (2 cases, 0.17%), and delayed hemopneumothorax (1 case, 0.09%). The median number of biopsy cores obtained was 3 (range: 1-7). Multivariate analysis revealed no evidence of an association between the number of cores and complications: hemoptysis (OR = 0.820, P = 0.410), pneumothorax (OR = 1.220, P = 0.663), intolerable pain (OR = 0.520, P = 0.387), vasovagal reaction (OR = 1.087, P = 0.924), hemothorax (OR = 1.062, P = 0.944), delayed hemopneumothorax (OR = 1.118, P = 0.930).

conclusionIn patients undergoing US-PLCNB for primary lung cancer, no evidence was found of an association between the core number biopsy samples obtained and post-procedural complications.

Indexed as

Image-Guided BiopsyLung NeoplasmsPostoperative ComplicationsAgedBiopsy, Large-Core NeedleChinaFemaleHemoptysisHumansMaleMiddle AgedPneumothoraxRetrospective StudiesUltrasonography, InterventionalComplicationsCore numberPrimary lung cancerUltrasound-guided percutaneous lung core needle biopsy(US-PLCNB)

Identifiers

PMID40817041
PMCPMC12355805

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.