Evidence map›Paper›PMID 40816834›Full record

ArticleJACC. Case reports2025

Defying the Odds: Survival After Amniotic Fluid Embolism and Extracorporeal Membrane Oxygenation Support.

Mariah Mascara, Andrea Caudill, Anantha S Madgula, Alysa Pivik, Saad Tabbara, Tyler VanDyck, Candice Lee, Masaki Tsukashita, Shan Modi, Karthikeyan Ranganathan

Abstract readCase Reports
In one paragraph

Article in JACC. Case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Mariah MascaraDepartment of Internal Medicine, Allegheny General Hospital, Pittsburgh, Pennsylvania, USA.
Andrea CaudillDepartment of Internal Medicine, Allegheny General Hospital, Pittsburgh, Pennsylvania, USA.
Anantha S MadgulaDepartment of Advanced Heart Failure, Cardiovascular Institute, Allegheny General Hospital, Pittsburgh, Pennsylvania, USA.
Alysa PivikDepartment of Advanced Heart Failure, Cardiovascular Institute, Allegheny General Hospital, Pittsburgh, Pennsylvania, USA.
Saad TabbaraDepartment of Interventional Cardiology, Cardiovascular Institute, Allegheny General Hospital, Pittsburgh, Pennsylvania, USA.
Tyler VanDyckDivision of Surgical Care and Cardiothoracic Surgical ICU, Allegheny General Hospital, Pittsburgh, Pennsylvania, USA.
Candice LeeDepartment of Cardiothoracic Surgery, Allegheny General Hospital, Pittsburgh, Pennsylvania, USA.
Masaki TsukashitaDepartment of Cardiothoracic Surgery, Allegheny General Hospital, Pittsburgh, Pennsylvania, USA.
Shan ModiDivision of Surgical Care and Cardiothoracic Surgical ICU, Allegheny General Hospital, Pittsburgh, Pennsylvania, USA.
Karthikeyan RanganathanDepartment of Advanced Heart Failure, Cardiovascular Institute, Allegheny General Hospital, Pittsburgh, Pennsylvania, USA; Department of Interventional Cardiology, Cardiovascular Institute, Allegheny General Hospital, Pittsburgh, Pennsylvania, USA. Electronic address: Karthikeyan.Ranganathan@ahn.org.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAmniotic fluid embolism is a rare potential complication in the peripartum period. CASE SUMMARY: A 27-year-old nulliparous woman presented for elective induction at 41 weeks' gestation. Due to nonreassuring fetal heart tracing, the patient underwent emergent caesarean section complicated by pulseless electrical activity arrest secondary to suspected amniotic fluid embolism after fetus delivery. Despite return of spontaneous circulation, the patient remained in cardiogenic shock with right ventricular failure. The patient was cannulated for venoarterial extracorporeal membrane oxygenation. After 5 days, she was converted to a right ventricular assist device, with ultimate complete biventricular recovery. DISCUSSION: The use of multidisciplinary cardiogenic shock team aids in swift escalation of care in patients with refractory shock requiring mechanical circulatory support. It is crucial to initiate cardiogenic shock teams early in a patient's clinical course. TAKE-HOME MESSAGES: Amniotic fluid embolism is a known cause of mortality in postpartum women. Severe cases can lead to cardiac arrest. Rapid initiation of mechanical circulatory support can save lives.

Indexed as

amniotic fluid embolismcritical careECMOmaternal survivalobstetric emergency

Identifiers

PMID40816834
PMCPMC12462143

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.