Evidence map›Paper›PMID 40816825›Full record

ArticleJACC. Case reports2025

Transcatheter Tricuspid Valve Replacement Beyond Boundaries.

Robin Le Ruz, Isaac George, Vratika Agarwal, Tamim Nazif, Mark Lebehn, Carolina Pinheiro Rezende, Torsten P Vahl, Martin B Leon, Rebecca T Hahn, Susheel K Kodali

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in JACC. Case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Robin Le RuzNantes Université, CHU Nantes, Interventional Cardiology Department, L'institut du thorax, Nantes, France; Nantes Université, CHU Nantes, CNRS, INSERM, L'institut du thorax, Nantes, France; Department of Medicine, Columbia University Irving Medical Center, New York, New York, USA. Electronic address: robin.leruz@chu-nantes.fr.
Isaac GeorgeDepartment of Medicine, Columbia University Irving Medical Center, New York, New York, USA.
Vratika AgarwalDepartment of Medicine, Columbia University Irving Medical Center, New York, New York, USA.
Tamim NazifDepartment of Medicine, Columbia University Irving Medical Center, New York, New York, USA.
Mark LebehnDepartment of Medicine, Columbia University Irving Medical Center, New York, New York, USA.
Carolina Pinheiro RezendeDepartment of Medicine, Columbia University Irving Medical Center, New York, New York, USA.
Torsten P VahlDepartment of Medicine, Columbia University Irving Medical Center, New York, New York, USA.
Martin B LeonDepartment of Medicine, Columbia University Irving Medical Center, New York, New York, USA.
Rebecca T HahnDepartment of Medicine, Columbia University Irving Medical Center, New York, New York, USA.
Susheel K KodaliDepartment of Medicine, Columbia University Irving Medical Center, New York, New York, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Transcatheter tricuspid valve replacement (TTVR) is now an available option to treat patients with severe symptomatic tricuspid regurgitation. Because of the early experience in this field, many challenges remain to be addressed. In this case series, we present 3 different situations that underline the difficulties in the clinical management of these patients. From a decision-making process standpoint, we discuss the relevance of TTVR in a patient presenting with an advanced cardiohepatic syndrome, as well as the case of a relatively young patient referred for tricuspid valve intervention following prior left-sided valves surgery. More from a technical and interventional strategy perspective, we describe a successful TTVR implantation after a failed transcatheter repair. TTVR has demonstrated convincing safety and efficacy results in large population samples. However, patient selection in clinical practice is still challenging, and this case series helps to refine our understanding of the role of TTVR in very specific clinical settings.

Indexed as

heart failureinterventional cardiologystructural heart diseasetricuspid regurgitation

Identifiers

PMID40816825
PMCPMC12462064

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.