Evidence map›Paper›PMID 40816660›Full record

ArticleCancer letters2025

Epithelial-YAP activation promotes wound-induced SCC in a TLR3-dependent microenvironment.

Yingchao Xue, Ru Dai, Elizabeth Winnicki, Amy van Ee, Charles Kirby, Chaewon Lee, Sashank K Reddy, Luis A Garza

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cancer letters, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yingchao XueDepartment of Dermatology, Johns Hopkins University, Baltimore, MD, 21231, USA. Electronic address: yxue8@jhmi.edu.
Ru DaiDepartment of Dermatology, Johns Hopkins University, Baltimore, MD, 21231, USA; Department of Dermatology, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, 310009, China.
Elizabeth WinnickiDepartment of Dermatology, Johns Hopkins University, Baltimore, MD, 21231, USA.
Amy van EeDepartment of Dermatology, Johns Hopkins University, Baltimore, MD, 21231, USA.
Charles KirbyDepartment of Dermatology, Johns Hopkins University, Baltimore, MD, 21231, USA.
Chaewon LeeDepartment of Dermatology, Johns Hopkins University, Baltimore, MD, 21231, USA.
Sashank K ReddyDepartment of Plastic and Reconstructive Surgery, Johns Hopkins University, Baltimore, MD, 21231, USA; Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD, 21231, USA; Institute for NanoBioTechnology, Johns Hopkins University, Baltimore, MD, 21231, USA. Electronic address: sreddy6@jhmi.edu.
Luis A GarzaDepartment of Dermatology, Johns Hopkins University, Baltimore, MD, 21231, USA; Department of Cell Biology, Johns Hopkins University, Baltimore, MD, 21231, USA; Department of Oncology, Johns Hopkins University, Baltimore, MD, 21231, USA. Electronic address: lag@jhmi.edu.

Funding

Technological Assessment and Solutions Core - RC4P30AG021334 · NIA · JOHNS HOPKINS UNIVERSITY · PI Jeremy D Walston · 2003 to 2026
$33.2M
Retinoic acid synthesis induced by noncoding dsRNA controls RegenerationR01AR074846 · NIAMS · JOHNS HOPKINS UNIVERSITY · PI GARZA, LUIS ANDRES · 2019 to 2023
$2.3M
Injection of autologous volar fibroblasts to the stump site to allow pressure adaptation and enhanced prosthetic use in amputeesUH3AR079376 · NIAMS · JOHNS HOPKINS UNIVERSITY · PI Luis Andres Garza · 2023 to 2026
$2.1M
Inhibition of regeneration restraining pathways to promote healingR01AR083822 · NIAMS · JOHNS HOPKINS UNIVERSITY · PI Luis Andres Garza · 2025 to 2026
$1.3M
NIAMS NIH HHS R01 AR074846NIAMS NIH HHS R01 AR083822NIAMS NIH HHS UH3 AR079376NIA NIH HHS P30 AG021334
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Squamous cell carcinoma (SCC)TLR3WoundingYAP

Identifiers

PMID40816660
PMCPMC12409731

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.