Evidence map›Paper›PMID 40816636›Full record

ArticleJournal of sport and health science2025

Low relative sit-to-stand power is associated with history of falls and fractures, prospective hospitalization, and all-cause mortality in older adults from the Toledo study for healthy aging.

Mikel Garcia-Aguirre, Ivan Baltasar-Fernandez, Julian Alcazar, Ana Alfaro-Acha, Fabio A Quiñonez-Bareiro, Ignacio Ara, Leocadio Rodriguez-Mañas, Francisco J Garcia-Garcia, Luis M Alegre

Abstract read
In one paragraph

Article in Journal of sport and health science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

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0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Mikel Garcia-AguirreGENUD Toledo Research Group, Faculty of Sport Sciences, University of Castilla-La Mancha, Toledo 45071, Spain; Centro de Investigación Biomédica en Red Fragilidad y Envejecimiento Saludable (CIBERFES), Instituto de Salud Carlos III, Madrid 28029, Spain; Instituto de Investigación Sanitaria de Castilla-La Mancha (IDISCAM), Junta de Comunidades de Castilla-La Mancha (JCCM), Toledo 45004, Spain; Grupo Mixto de Fragilidad y Envejecimiento Exitoso Universidad de Castilla-La Mancha-Servicio de Salud de Castilla-La Mancha (UCLM-SESCAM), Toledo 45007, Spain.
Ivan Baltasar-FernandezGENUD Toledo Research Group, Faculty of Sport Sciences, University of Castilla-La Mancha, Toledo 45071, Spain; Centro de Investigación Biomédica en Red Fragilidad y Envejecimiento Saludable (CIBERFES), Instituto de Salud Carlos III, Madrid 28029, Spain; Instituto de Investigación Sanitaria de Castilla-La Mancha (IDISCAM), Junta de Comunidades de Castilla-La Mancha (JCCM), Toledo 45004, Spain; Grupo Mixto de Fragilidad y Envejecimiento Exitoso Universidad de Castilla-La Mancha-Servicio de Salud de Castilla-La Mancha (UCLM-SESCAM), Toledo 45007, Spain; Faculty of Health Sciences, University of Castilla-La Mancha, Talavera de la Reina 45600, Spain.
Julian AlcazarGENUD Toledo Research Group, Faculty of Sport Sciences, University of Castilla-La Mancha, Toledo 45071, Spain; Centro de Investigación Biomédica en Red Fragilidad y Envejecimiento Saludable (CIBERFES), Instituto de Salud Carlos III, Madrid 28029, Spain; Instituto de Investigación Sanitaria de Castilla-La Mancha (IDISCAM), Junta de Comunidades de Castilla-La Mancha (JCCM), Toledo 45004, Spain; Grupo Mixto de Fragilidad y Envejecimiento Exitoso Universidad de Castilla-La Mancha-Servicio de Salud de Castilla-La Mancha (UCLM-SESCAM), Toledo 45007, Spain.
Ana Alfaro-AchaCentro de Investigación Biomédica en Red Fragilidad y Envejecimiento Saludable (CIBERFES), Instituto de Salud Carlos III, Madrid 28029, Spain; Instituto de Investigación Sanitaria de Castilla-La Mancha (IDISCAM), Junta de Comunidades de Castilla-La Mancha (JCCM), Toledo 45004, Spain; Grupo Mixto de Fragilidad y Envejecimiento Exitoso Universidad de Castilla-La Mancha-Servicio de Salud de Castilla-La Mancha (UCLM-SESCAM), Toledo 45007, Spain; Geriatrics Department, Hospital Universitario de Toledo, Toledo 45071, Spain.
Fabio A Quiñonez-BareiroCentro de Investigación Biomédica en Red Fragilidad y Envejecimiento Saludable (CIBERFES), Instituto de Salud Carlos III, Madrid 28029, Spain; Instituto de Investigación Sanitaria de Castilla-La Mancha (IDISCAM), Junta de Comunidades de Castilla-La Mancha (JCCM), Toledo 45004, Spain; Grupo Mixto de Fragilidad y Envejecimiento Exitoso Universidad de Castilla-La Mancha-Servicio de Salud de Castilla-La Mancha (UCLM-SESCAM), Toledo 45007, Spain; Geriatrics Department, Hospital Universitario de Toledo, Toledo 45071, Spain.
Ignacio AraGENUD Toledo Research Group, Faculty of Sport Sciences, University of Castilla-La Mancha, Toledo 45071, Spain; Centro de Investigación Biomédica en Red Fragilidad y Envejecimiento Saludable (CIBERFES), Instituto de Salud Carlos III, Madrid 28029, Spain; Instituto de Investigación Sanitaria de Castilla-La Mancha (IDISCAM), Junta de Comunidades de Castilla-La Mancha (JCCM), Toledo 45004, Spain; Grupo Mixto de Fragilidad y Envejecimiento Exitoso Universidad de Castilla-La Mancha-Servicio de Salud de Castilla-La Mancha (UCLM-SESCAM), Toledo 45007, Spain.
Leocadio Rodriguez-MañasCentro de Investigación Biomédica en Red Fragilidad y Envejecimiento Saludable (CIBERFES), Instituto de Salud Carlos III, Madrid 28029, Spain; Geriatrics Department, Getafe University Hospital, Getafe 28905, Spain.
Francisco J Garcia-GarciaCentro de Investigación Biomédica en Red Fragilidad y Envejecimiento Saludable (CIBERFES), Instituto de Salud Carlos III, Madrid 28029, Spain; Instituto de Investigación Sanitaria de Castilla-La Mancha (IDISCAM), Junta de Comunidades de Castilla-La Mancha (JCCM), Toledo 45004, Spain; Grupo Mixto de Fragilidad y Envejecimiento Exitoso Universidad de Castilla-La Mancha-Servicio de Salud de Castilla-La Mancha (UCLM-SESCAM), Toledo 45007, Spain; Geriatrics Department, Hospital Universitario de Toledo, Toledo 45071, Spain. Electronic address: franjogarcia@telefonica.net.
Luis M AlegreGENUD Toledo Research Group, Faculty of Sport Sciences, University of Castilla-La Mancha, Toledo 45071, Spain; Centro de Investigación Biomédica en Red Fragilidad y Envejecimiento Saludable (CIBERFES), Instituto de Salud Carlos III, Madrid 28029, Spain; Instituto de Investigación Sanitaria de Castilla-La Mancha (IDISCAM), Junta de Comunidades de Castilla-La Mancha (JCCM), Toledo 45004, Spain; Grupo Mixto de Fragilidad y Envejecimiento Exitoso Universidad de Castilla-La Mancha-Servicio de Salud de Castilla-La Mancha (UCLM-SESCAM), Toledo 45007, Spain. Electronic address: luis.alegre@uclm.es.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLow relative sit-to-stand (STS) power has emerged as a critical predictor of adverse health outcomes, such as frailty and disability, in older adults. However, its impact on falls, fractures, hospitalizations, and all-cause mortality remains unclear. Therefore, this longitudinal study aimed to investigate the potential associations between low relative STS power and these adverse health outcomes in older adults.

methodsA total of 1876 older adults (aged ≥65 years, 56.4% women) were included from the Toledo Study for Healthy Aging. Relative STS power was assessed using the 30-s STS test and the Alcazar equation. Participants were categorized as having low relative STS power based on previously established cut-off points (2.53 W/kg for men and 2.01 W/kg for women). Falls and fractures (hip and all-type) within the previous year were recorded. Hospitalizations and all-cause mortality were obtained during a follow-up of 6.8 ± 3.1 years (mean ± SD; median = 7.8 years; interquartile range: 3.9-10.1 years) and 9.7 ± 3.5 years (median = 10.9 years; interquartile range: 8.2-12.5 years), respectively. Generalized linear mixed models, binary logistic regression, and proportional hazards regression adjusted for age, educational level, and comorbidities were used.

resultsIn men, low relative STS power was significantly associated with an increased likelihood of history of falls (odds ratio (OR) = 1.73, 95% confidence interval (95%CI): 1.08-2.75, p = 0.022) and all-type fractures (OR = 1.86, 95%CI:1.21-2.84, p = 0.004) in the previous year. In women, low relative STS power was associated with a higher probability of hip fractures within the previous year (OR = 3.25, 95%CI: 1.07-9.86, p = 0.038). Low relative STS power predicted hospitalizations in women (hazard ratio (HR) = 1.29, 95%CI: 1.06-1.58, p = 0.012) and longer hospital stays in both men (p = 0.020) and women (p = 0.033). Low relative STS power significantly increased all-cause mortality in both men (HR = 1.57, 95%CI: 1.26-1.97, p < 0.001) and women (HR = 2.04, 95%CI: 1.51-2.74, p < 0.001).

conclusionLow relative STS power was associated with history of hip fractures in women, whereas in men it was associated with history of falls and all-type fractures. Low relative STS power predicted hospitalizations in women but not in men. In both men and women, low relative STS power was associated with longer hospital stays and increased risk of all-cause mortality.

Indexed as

Adverse outcomesDisabilityFrailtyHospitalization stayMuscle power

Identifiers

PMID40816636
PMCPMC12914193

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