Evidence map›Paper›PMID 40816456›Full record

ArticleDevelopmental biology2025

HOXA5-driven transcriptional program in lung development.

Béatrice Frenette, Josselin Guéno, Nicolas Houde, Jennifer H Mansfield, Lucie Jeannotte

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Developmental biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Béatrice FrenetteDepartment of Molecular Biology, Medical Biochemistry & Pathology, Université Laval, Québec, Canada.
Josselin GuénoDepartment of Molecular Biology, Medical Biochemistry & Pathology, Université Laval, Québec, Canada.
Nicolas HoudeCentre de recherche sur le cancer de l'Université Laval, Centre de recherche du CHU de Québec-Université Laval (Oncology), Québec, Canada.
Jennifer H MansfieldDepartment of Biology, Barnard College, Columbia University, New York, USA.
Lucie JeannotteDepartment of Molecular Biology, Medical Biochemistry & Pathology, Université Laval, Québec, Canada; Centre de recherche sur le cancer de l'Université Laval, Centre de recherche du CHU de Québec-Université Laval (Oncology), Québec, Canada. Electronic address: lucie.jeannotte@crchudequebec.ulaval.ca.

Funding

Testing the tissue-specific mechanisms of Hoxa5 function in musculoskeletal patterningR15HD092179 · NICHD · BARNARD COLLEGE · PI MANSFIELD, JENNIFER H · 2017 to 2017
$389k
NICHD NIH HHS R15 HD092179
6 · The paper itself

Abstract

Despite the fundamental role of Hoxa5 in mouse development revealed by the well-characterized phenotypes of Hoxa5 mutant mice, HOXA5-dependent regulatory networks remain ill-defined. We generated a Hoxa5

Indexed as

Homeodomain ProteinsLungTranscription FactorsAnimalsChromatin Immunoprecipitation SequencingFibroblast Growth Factor 10Gene Expression Regulation, DevelopmentalMiceMice, KnockoutOrganogenesisTranscription, GeneticFgf10 protein, mouseFibroblast Growth Factor 10Homeodomain ProteinsHoxa5 protein, mouseTranscription FactorsDevelopmentHOXA5HOX targetsLung

Identifiers

PMID40816456
PMCPMC13255264

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.