Evidence map›Paper›PMID 40816435›Full record

ArticleContemporary clinical trials2025

COVID Prevention Program: Rationale and methodology of a tailored behavioral intervention to prevent household and community spread of COVID-19 among Latinos.

Noe C Crespo, Job Godino, Alma Behar, Patricia Dionicio, Carolina Lopez de la Torre, Kiria Fraga, Marco Santoscoy, John P Elder, Eyal Oren, Chii-Dean Lin and 3 more

Registry-linked trialAbstract readClinical Trial Protocol
In one paragraph

Article in Contemporary clinical trials, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05697068 (Tailored Behavioral Intervention to Prevent Household and Community Spread of COVID-19 Among Latinos), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05697068 naactive not recruitingnot on this map

Tailored Behavioral Intervention to Prevent Household and Community Spread of COVID-19 Among Latinos

TypeinterventionalSponsorSan Diego State UniversityRan2022 to 2025Enrolled256ConditionsSARS-CoV-2 InfectionArmsCOVID Prevention Program (CPP)
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Noe C CrespoInstitute for Behavioral and Community Health, 9245 Sky Park Court, Suite 221, San Diego, CA 92123, USA; San Diego State University, School of Public Health, 5500 Campanile Drive, San Diego, CA 92182, USA. Electronic address: ncrespo@sdsu.edu.
Job GodinoInstitute for Behavioral and Community Health, 9245 Sky Park Court, Suite 221, San Diego, CA 92123, USA; Family Health Centers of San Diego, 823 Gateway Center Way, San Diego, CA 92102, USA.
Alma BeharInstitute for Behavioral and Community Health, 9245 Sky Park Court, Suite 221, San Diego, CA 92123, USA; San Diego State University, School of Public Health, 5500 Campanile Drive, San Diego, CA 92182, USA.
Patricia DionicioInstitute for Behavioral and Community Health, 9245 Sky Park Court, Suite 221, San Diego, CA 92123, USA; San Diego State University, School of Public Health, 5500 Campanile Drive, San Diego, CA 92182, USA.
Carolina Lopez de la TorreInstitute for Behavioral and Community Health, 9245 Sky Park Court, Suite 221, San Diego, CA 92123, USA; San Diego State University, Department of Psychology, 5500 Campanile Drive, San Diego, CA 92182, USA.
Kiria FragaInstitute for Behavioral and Community Health, 9245 Sky Park Court, Suite 221, San Diego, CA 92123, USA; San Diego State University, School of Public Health, 5500 Campanile Drive, San Diego, CA 92182, USA.
Marco SantoscoyInstitute for Behavioral and Community Health, 9245 Sky Park Court, Suite 221, San Diego, CA 92123, USA.
John P ElderInstitute for Behavioral and Community Health, 9245 Sky Park Court, Suite 221, San Diego, CA 92123, USA; San Diego State University, School of Public Health, 5500 Campanile Drive, San Diego, CA 92182, USA.
Eyal OrenInstitute for Behavioral and Community Health, 9245 Sky Park Court, Suite 221, San Diego, CA 92123, USA; San Diego State University, School of Public Health, 5500 Campanile Drive, San Diego, CA 92182, USA.
Chii-Dean LinSan Diego State University, Department of Mathematics and Statistics, 5500 Campanile Drive, San Diego, CA 92182, USA.
Elva M ArredondoInstitute for Behavioral and Community Health, 9245 Sky Park Court, Suite 221, San Diego, CA 92123, USA; San Diego State University, Department of Psychology, 5500 Campanile Drive, San Diego, CA 92182, USA.
Hala MadanatInstitute for Behavioral and Community Health, 9245 Sky Park Court, Suite 221, San Diego, CA 92123, USA; San Diego State University, School of Public Health, 5500 Campanile Drive, San Diego, CA 92182, USA; Division of Research and Innovation, San Diego State University, 5500 Campanile Drive, San Diego, CA, USA.
Christian B RamersSan Diego State University, School of Public Health, 5500 Campanile Drive, San Diego, CA 92182, USA; Family Health Centers of San Diego, 823 Gateway Center Way, San Diego, CA 92102, USA.

Funding

Building Capacity and Infrastructure for Population Health and Health Disparities Research at San Diego State UniversityS21MD010690 · NIMHD · SAN DIEGO STATE UNIVERSITY · PI AYALA, GUADALUPE X, CASTILLO, JOSE E · 2016 to 2020
$10.0M
Tailored Behavioral Intervention to Prevent Household and Community Spread of COVID-19 among LatinosR01MD016324 · NIMHD · SAN DIEGO STATE UNIVERSITY · PI CRESPO, NOE CUAUHTEMOC, RAMERS, CHRISTIAN B · 2021 to 2025
$3.1M
NIMHD NIH HHS R01 MD016324NIMHD NIH HHS S21 MD010690
6 · The paper itself

Abstract

backgroundCOVID-19 has disproportionately affected underserved communities, such as Latinos living in the U.S. Promotoras (Community Health Workers) may be effective at delivering tailored and culturally relevant strategies to prevent household spread and the burden of SARS-CoV-2 among Latinos and other minority groups. PURPOSE: To develop, implement, and test the clinic-based promotora-led COVID-19 Prevention Program (CPP) to reduce transmission of SARS-CoV-2 in 256 Latino households and the community.

designCPP is a two-group randomized controlled trial designed to test the immediate, mid-term, and long-term effectiveness of the promotora-led intervention, as well as test its effectiveness on short- and long-term behavioral, mental, and physical health outcomes. The primary outcome is household infection rate assessed at 6 weeks and 6-, 12-, and 24-months based on a binary indicator (yes vs. no) of evidence of a new infection via antigen, real-time reverse transcriptase-polymerase chain reaction (RT-PCR), or antibody SARS-CoV-2 test results within household members. Patients in the intervention group will receive enhanced standard-of-care, including tailored, real-time text messaging and virtual counseling, delivered by promotoras. Patients in the control group will receive the clinical standard of care. Analyses will test for household-level group differences in new infections related to an identified index case. DISCUSSION: Preventing household spread of SARS-CoV-2 is an important strategy to reduce the overall burden of SARS-CoV-2 among Latinos. The CPP is a scalable and tailored approach that has the potential to serve as a model to address future respiratory disease outbreaks, especially among uninsured, low-income, and medically underserved communities.

trial registrationClinicaltrials.gov Identifier NCT05697068 (1/20/2023).

Indexed as

Community Health WorkersCOVID-19Health PromotionHispanic or LatinoAdultFamily CharacteristicsFemaleHumansMaleMiddle AgedRandomized Controlled Trials as TopicUnited StatesBehaviorCommunity health workersHealth CenterHispanicsPreventionSARS-CoV-2

Identifiers

PMID40816435
PMCPMC12751378

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.