Evidence map›Paper›PMID 40816372›Full record

ArticleIndian pacing and electrophysiology journal

Successful use of Closed Loop Stimulation pacemaker for carotid sinus syndrome due to infiltrating neck cancer.

Stefano Maffè, Paola Paffoni, Luca Bergamasco, Pierfranco Dellavesa

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Indian pacing and electrophysiology journal. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Sensor detection and pacing for impending reflex syncope.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2026
    Review
  2. Closed loop stimulation for carotid sinus syncope.Indian pacing and electrophysiology journal
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Stefano MaffèDivision of Cardiology, SS Trinita' Borgomanero Hospital, ASL NO, Novara, Italy. Electronic address: stemaffe@libero.it.
Paola PaffoniDivision of Cardiology, SS Trinita' Borgomanero Hospital, ASL NO, Novara, Italy.
Luca BergamascoDivision of Cardiology, SS Trinita' Borgomanero Hospital, ASL NO, Novara, Italy.
Pierfranco DellavesaDivision of Cardiology, SS Trinita' Borgomanero Hospital, ASL NO, Novara, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 64-year-old male with oropharyngeal carcinoma experienced recurrent syncope and hypotension due to neoplastic compression of the right carotid space. Despite initial treatment with atropine and fluid resuscitation, the patient continued to experience presyncope and hypotensive events. After treatment with a conventional dual-chamber pacemaker failed, the use of closed-loop stimulation (CLS) successfully resolved the syncope episodes. This case highlights the efficacy of CLS pacing in managing reflex syncope caused by extrinsic neoplastic compression of the carotid sinus. The CLS algorithm, by detecting pre-syncopal phases and increasing heart rate proactively, offers a significant advantage over conventional pacing in preventing syncope.

Indexed as

Cancer patientCarotid sinus syndromeClosed loop stimulationPacemaker

Identifiers

PMID40816372
PMCPMC12461721

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.