Evidence map›Paper›PMID 40816285›Full record

ArticleCurrent biology : CB2025

Linear covariation between germline and somatic mutation rates across ciliates and mammals.

Guangying Wang, Lu Fu, Wei Miao, Jianzhi Zhang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Current biology : CB, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Evolution of the highest fidelity DNA replication systems.bioRxiv : the preprint server for biology · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Guangying WangInstitute of Hydrobiology, Chinese Academy of Sciences, Wuhan 430072, China; Department of Ecology and Evolutionary Biology, University of Michigan, Ann Arbor, MI 48109, USA.
Lu FuInstitute of Hydrobiology, Chinese Academy of Sciences, Wuhan 430072, China.
Wei MiaoInstitute of Hydrobiology, Chinese Academy of Sciences, Wuhan 430072, China; State Key Laboratory of Breeding Biotechnology and Sustainable Aquaculture, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan 430072, China. Electronic address: miaowei@ihb.ac.cn.
Jianzhi ZhangDepartment of Ecology and Evolutionary Biology, University of Michigan, Ann Arbor, MI 48109, USA. Electronic address: jianzhi@umich.edu.

Funding

Genomic and Systemic Approaches to Evolutionary MechanismsR35GM139484 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI JIANZHI ZHANG · 2021 to 2026
$3.2M
NIGMS NIH HHS R35 GM139484
6 · The paper itself

Abstract

Somatic mutations have received increased attention due to their roles in disease (e.g., cancer) and possibly aging.

Indexed as

Germ-Line MutationMammalsMutation RateTetrahymena thermophilaAnimalsCiliophoraGerm Cellsciliateevolutiongermline mutation ratemammalmutation accumulationpleiotropysomatic mutation rateTetrahymena thermophila

Identifiers

PMID40816285
PMCPMC12888776

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.