Evidence map›Paper›PMID 40815678›Full record

ArticleOrganic letters2025

Biosynthesis of Antituberculosis Antibiotic Capreomycin Involves a

Yi-Ting Lai, Chun-Yu Peng, Hsiao-Tzu Liao, Po-Yun Hsiao, Chang-Ko Hsieh, Yu-Ru Luo, Sheng-Cih Huang, Yung-Lin Wang, Thomas Ma, Ya-Rong Chen and 4 more

Abstract read
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In one paragraph

Article in Organic letters, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Yi-Ting LaiDepartment of Biological Science and Technology, National Yang Ming Chiao Tung University, Hsinchu 30010, Taiwan.
Chun-Yu PengDepartment of Biological Science and Technology, National Yang Ming Chiao Tung University, Hsinchu 30010, Taiwan.
Hsiao-Tzu LiaoDepartment of Biological Science and Technology, National Yang Ming Chiao Tung University, Hsinchu 30010, Taiwan.
Po-Yun HsiaoDepartment of Biological Science and Technology, National Yang Ming Chiao Tung University, Hsinchu 30010, Taiwan.
Chang-Ko HsiehDepartment of Biological Science and Technology, National Yang Ming Chiao Tung University, Hsinchu 30010, Taiwan.
Yu-Ru LuoDepartment of Biological Science and Technology, National Yang Ming Chiao Tung University, Hsinchu 30010, Taiwan.
Sheng-Cih HuangDepartment of Applied Chemistry, National Yang Ming Chiao Tung University, Hsinchu 30010, Taiwan.
Yung-Lin WangGenomics Research Center, Academia Sinica, Taipei 11529, Taiwan.
Thomas MaDepartment of Chemistry, National Taiwan University, Taipei 10617, Taiwan.
Ya-Rong ChenDepartment of Chemistry, National Taiwan University, Taipei 10617, Taiwan.
You-Min KuoDepartment of Biological Science and Technology, National Yang Ming Chiao Tung University, Hsinchu 30010, Taiwan.
Yen-Cheng LinDepartment of Biological Science and Technology, National Yang Ming Chiao Tung University, Hsinchu 30010, Taiwan.
John ChuDepartment of Chemistry, National Taiwan University, Taipei 10617, Taiwan.ORCID 0000-0002-7033-7229
Chin-Yuan ChangDepartment of Biological Science and Technology, National Yang Ming Chiao Tung University, Hsinchu 30010, Taiwan.ORCID 0000-0001-7314-3967

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Capreomycin (CMN) is a nonribosomal peptide (NRP) antituberculosis antibiotic. CMN biosynthesis involves a non-canonical

Indexed as

Antibiotics, AntitubercularAntitubercular AgentsCapreomycinPeptide SynthasesMolecular StructureAntibiotics, AntitubercularAntitubercular AgentsCapreomycinnon-ribosomal peptide synthasePeptide Synthases

Identifiers

PMID40815678
PMCPMC12400406

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.