Evidence map›Paper›PMID 40815649›Full record

ArticleScience advances2025

Super-resolution triple-resonance NMR spectroscopy for the sequential assignment of proteins.

Olivia Gampp, Luca Wenchel, Peter Güntert, Piotr Klukowski, Roland Riek

Abstract read
In one paragraph

Article in Science advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Super-Resolution solid-state NMR Spectroscopy.Journal of biomolecular NMR · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Olivia GamppInstitute of Molecular Physical Science, ETH Zürich, Vladimir-Prelog-Weg 2, CH-8093 Zürich, Switzerland.ORCID 0009-0004-8130-6825
Luca WenchelInstitute of Molecular Physical Science, ETH Zürich, Vladimir-Prelog-Weg 2, CH-8093 Zürich, Switzerland.ORCID 0009-0008-6739-125X
Peter GüntertInstitute of Molecular Physical Science, ETH Zürich, Vladimir-Prelog-Weg 2, CH-8093 Zürich, Switzerland.ORCID 0000-0002-2911-7574
Piotr KlukowskiInstitute of Molecular Physical Science, ETH Zürich, Vladimir-Prelog-Weg 2, CH-8093 Zürich, Switzerland.ORCID 0000-0003-1045-3487
Roland RiekDepartment of Chemistry, Tokyo Metropolitan University, Hachioji, 192-0397 Tokyo, Japan.ORCID 0000-0002-6333-066X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To study the structure and dynamics of proteins by nuclear magnetic resonance (NMR), sequence-specific assignment is needed, which can be obtained by acquiring and analyzing multiple triple-resonance experiments with the three-dimensional TROSY-HNCA, the most sensitive stand-alone experiment with which sequential assignment is, in principle, possible. However, gaining an unambiguous assignment solely from this spectrum is generally not possible because amino acid-type information cannot be gleaned only from the

Indexed as

Nuclear Magnetic Resonance, BiomolecularProteinsCarbon IsotopesMagnetic Resonance SpectroscopyCarbon IsotopesProteins

Identifiers

PMID40815649
PMCPMC12356247

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.