SynthesisThe Laryngoscope2026
Anxiety and Depression in Adults With Vestibular Disorders: A Systematic Review and Meta-Analysis.
Synthesis in The Laryngoscope, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Anxiety and Depression in Adults With Vestibular Disorders: A Systematic Review and Meta-Analysis.The Laryngoscope · 2026Pooled it
- Rimegepant for vestibular and cochlear symptoms associated with vertigo in a real-world retrospective study.iScience · 2026Article
- Long-Term DHI Outcomes in Patients with Chronic Dizziness and Initially Uncertain Diagnosis: A Retrospective Follow-Up Study.Audiology research · 2026Article
- Posterior insular cortex hyperactivation drives vestibular migraine and comorbid anxiety.The journal of headache and pain · 2026Article
- The Impact of Genetic Factors in Ménière's Disease.International journal of molecular sciences · 2026Review
- PTSD and Audio Vestibular Symptoms: A Two-Way Street Driven by the Amygdala? A Speculative Hypothesis.Brain sciences · 2026Review
- The effect of combined cognitive behavioral therapy and rehabilitation training on negative emotions of patients with vestibular dysfunction: a real-world cohort study.Frontiers in public health · 2026Article
- Machine learning analysis of posturography in panic disorder: a pilot study for objective physiological biomarker identification.Frontiers in psychiatry · 2025Article
- Comorbidities and impact on quality of life in patients with Ménière's disease: a single-center cross-sectional study.Frontiers in neurologyArticle
- Toward personalized medicine for mal de débarquement syndrome.Frontiers in neurologyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo derive precise estimates of anxiety and depressive disorder prevalence in patients with common vestibular disorders. DATA SOURCES: CINAHL, Cochrane Library, PubMed, PsycINFO, and SCOPUS. REVIEW
methodsThis systematic review and meta-analysis was reported per PRISMA guidelines. Outcomes included continuous measures (mean), proportions (%), and relative risks (RR) with 95% confidence intervals.
resultsEighty-five studies (n = 764,403) examining anxiety, depression, and vestibular disorders in adults were included. Mean ages were 50.3 (vestibular) and 46.7 (control); females comprised 63.8% and 64.3%, respectively. Patients with vestibular disorders had significantly higher rates and risks of anxiety (31.4% vs. 8.3%, p < 0.0001; RR = 1.50, 95% CI: 1.1-2.0) and depression (28.3% vs. 4.7%, p < 0.0001; RR = 2.9, 95% CI: 1.8-4.4) than controls. Elevated rates were observed in benign paroxysmal positional vertigo (30.6%, 23.6%), Meniere's disease (47.0%, 43.1%), vestibular migraine (46.5%, 35.7%), and vestibular neuritis (19.4%, 20.7%) (all p < 0.0001). Episodic disorders showed higher prevalence than vestibular neuritis. Patients with unspecified peripheral vestibular disorders also had significantly higher anxiety (12.1%) and depression (13.2%) rates than controls. Meta-regression revealed significant associations between Dizziness Handicap Inventory (DHI) scores and Hospital Anxiety and Depression Scale (HADS) anxiety and depression subscales.
conclusionsThis meta-analysis offers the most precise prevalence and relative risk estimates of anxiety and depressive disorders in vestibular illness. The greater risk in episodic versus single-event vestibular disorders may inform the understanding of vestibular-psychiatric comorbidity mechanisms.
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