Evidence map›Paper›PMID 40815477›Full record

ArticlemSystems2025

Metabolic remodeling of microorganisms by mobile genetic elements alters mutualistic community composition.

Ave T Bisesi, Ross P Carlson, Lachlan Cotner, William R Harcombe

Abstract read
In one paragraph

Article in mSystems, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ave T BisesiDepartment of Ecology, Evolution and Behavior, University of Minnesota, St. Paul, Minnesota, USA.ORCID 0000-0001-9076-7384
Ross P CarlsonDepartment of Chemical and Biological Engineering, Montana State University, Bozeman, Montana, USA.ORCID 0000-0002-2464-7111
Lachlan CotnerDepartment of Ecology, Evolution and Behavior, University of Minnesota, St. Paul, Minnesota, USA.
William R HarcombeDepartment of Ecology, Evolution and Behavior, University of Minnesota, St. Paul, Minnesota, USA.ORCID 0000-0001-8445-2052

Funding

National Science Foundation 2019304National Science Foundation 2226051
6 · The paper itself

Abstract

Mobile genetic elements (MGEs) are ubiquitous in prokaryotes and exert significant influence on microbial communities, in part through their effects on host metabolism. While some MGEs directly alter host metabolism by introducing novel enzymes, all MGEs can indirectly change bacterial metabolism by redirecting intracellular host resources away from native bacterial processes toward MGE production. As a result, even when MGEs do not provide new metabolic functions, their carriage can influence host traits such as growth rate, nutrient uptake, and waste excretion, with consequences for how bacteria contribute to community and ecosystem functions. However, there are few empirical tests of how the indirect metabolic consequences of MGE carriage shape interactions between host and non-host bacterial species. We integrated genome-scale metabolic modeling with an

Indexed as

Escherichia coliInterspersed Repetitive SequencesMicrobiotaSymbiosisSalmonella entericaconjugationfilamentous bacterial virusmetabolic modelingmicrobial communitiesplasmid

Identifiers

PMID40815477
PMCPMC12455974

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.