ArticleFish physiology and biochemistry2025
Thyme-synthesized silver nanoparticles mitigate immunosuppression, oxidative damage, and histopathological alterations induced by multidrug-resistant Enterococcus faecalis in Oreochromis niloticus: in vitro and in vivo assays.
Article in Fish physiology and biochemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Green Synthesis of Silver Nanoparticles Using Artemisia vestita: Phytochemical Insights and Bioactivity Against Fish Pathogens.Chemistry & biodiversity · 2026Article
- Protective effects of Astragalus membranaceus polysaccharide against aluminum oxide nanoparticle-induced growth retardation and oxidative-immunological disruption in Oreochromis niloticus.Scientific reports · 2026Article
- Biological Functions of Silver Nanowires in InhibitingLife (Basel, Switzerland) · 2026Article
- Nano-curcumin mitigates aluminum oxide nanoparticle toxicity in Nile tilapia through antioxidant and immune modulation.Fish physiology and biochemistry · 2026Article
- Synchronous natural infection of Nile tilapia (Oreochromis niloticus) by drug-resistant Pseudomonas aeruginosa and Saprolegnia parasitica: insights into water quality, phenotypic traits, and genotypic profiles.Veterinary research communications · 2025Article
- Effects ofAnimals : an open access journal from MDPI · 2025Article
- Bacterial Pathogens and Their Antimicrobial Resistance in Farmed Nile Tilapia Experiencing "Summer Mortality" in Kafr El-Sheikh, Egypt.Microorganisms · 2025Article
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Authors and funding
9 authors.
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Abstract
The escalating prevalence of antibiotic resistance poses a significant challenge to controlling aquatic diseases, underscoring the need for innovative antimicrobial approaches. Therefore, the current study aimed to investigate the effects of thyme-synthesized silver nanoparticles (thyme-AgNPs) on modulating the immunosuppressive, oxidative stress, and histopathological changes induced by multidrug-resistant Enterococcus faecalis (MDR E. faecalis) infection in Oreochromis niloticus (Nile tilapia). The antibiotic susceptibility profiling of the isolated E. faecalis (PQ084785) revealed resistance to multiple antibiotic classes. The in vitro bactericidal efficacy of thyme-AgNPs was confirmed, with minimum bactericidal concentrations (MBC) and minimum inhibitory concentrations (MIC) of 62.5 µg/mL and 31.5 µg/mL, respectively. In vivo, the 96-h median lethal concentration (LC
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