Evidence map›Paper›PMID 40815093›Full record

ArticlePreventing chronic disease2025

E-Cigarette Use and Symptoms of Depression and Anxiety Among US Middle and High School Students.

Brenna VanFrank, Tonya R Williams, Iris C Alcantara, Marci Hertz, Maeh Al-Shawaf, Christina Meyers, Andrenita West

Abstract read
In one paragraph

Article in Preventing chronic disease, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Electronic cigarettes: isolated and combined use among Brazilian adolescents in PeNSE 2019.Revista brasileira de epidemiologia = Brazilian journal of epidemiology · 2026
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Brenna VanFrankOffice on Smoking and Health, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia.
Tonya R WilliamsOffice on Smoking and Health, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia.
Iris C AlcantaraOffice on Smoking and Health, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia.
Marci HertzDivision of Adolescent and School Health, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia.
Maeh Al-ShawafOffice on Smoking and Health, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia.
Christina MeyersOffice on Smoking and Health, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia.
Andrenita WestOffice on Smoking and Health, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: E-cigarettes are the most commonly used tobacco product among youth. Most e-cigarettes contain nicotine, which is highly addictive and can harm the developing brain. Youth e-cigarette use is associated with poor mental health. Methods: We analyzed self-reported data from the 2024 National Youth Tobacco Survey to describe e-cigarette use and symptoms of depression and anxiety among US middle and high school students. Results: In 2024, 42.1% of youth who currently used e-cigarettes reported moderate-to-severe symptoms of depression and anxiety compared with 21.0% of youth who never or formerly used e-cigarettes. Among youth who currently used e-cigarettes, those with moderate-to-severe symptoms of depression and anxiety (vs no-to-mild symptoms) more frequently reported symptoms of dependence - wanting to use an e-cigarette within 30 minutes of waking (28.2% vs 15.6%, P < .001) and having strong cravings (37.6% vs 22.4%, P < .001) - and "feeling anxious, stressed, or depressed" as a reason for first (41.8% vs 18.4%, P < .001) and current (51.0% vs 25.2%, P < .001) use. Most youth who used e-cigarettes attempted to quit in the past year (69.4%), but over half (58.5%) did not use any quitting resources. Conclusion: Moderate-to-severe symptoms of depression and anxiety are common among youth who use e-cigarettes. Youth with these symptoms may need additional support to prevent or quit e-cigarette use. Integrating mental health support into comprehensive approaches to tobacco use prevention and cessation, paired with strengthening the foundations of healthy communities for youth, may reduce youth e-cigarette use.

Indexed as

AnxietyDepressionElectronic Nicotine Delivery SystemsStudentsVapingAdolescentFemaleHumansMaleSelf ReportUnited States

Identifiers

PMID40815093
PMCPMC12360061

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.