Evidence map›Paper›PMID 40814516›Full record

ArticleJournal of family medicine and primary care2025

Metronidazole-induced cerebellar dysfunction: An underdiagnosed identity.

Aditya Debuka, Manaswi Chaubey, Shubh N T Rai, Ajay Gupta, Jaya Chakravarty

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of family medicine and primary care, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Aditya DebukaDepartment of Medicine, Institute of Medical Sciences, Banaras Hindu University, Varanasi, Uttar Pradesh, India.
Manaswi ChaubeyDepartment of Medicine, Institute of Medical Sciences, Banaras Hindu University, Varanasi, Uttar Pradesh, India.
Shubh N T RaiDepartment of Medicine, Institute of Medical Sciences, Banaras Hindu University, Varanasi, Uttar Pradesh, India.
Ajay GuptaDepartment of Medicine, Institute of Medical Sciences, Banaras Hindu University, Varanasi, Uttar Pradesh, India.
Jaya ChakravartyDepartment of Medicine, Institute of Medical Sciences, Banaras Hindu University, Varanasi, Uttar Pradesh, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Metronidazole is a commonly used antibiotic in clinical practice. It is associated with neurological toxicity if used for a longer duration or at a higher dose. In our case, the patient was prescribed metronidazole for the treatment of amoebic liver abscess for 7 weeks and he developed metronidazole-induced cerebellar dysfunction and small fibre peripheral neuropathy. Characteristic MRI findings, temporal association of symptoms with drug and resolution on drug withdrawal helped to make the diagnosis. Our case highlights the need of avoidance of prolonged administration of metronidazole and advocates alternative methods including percutaneous drainage to be adopted for a nonresolving liver abscess.

Indexed as

Ataxiacerebellummetronidazoleperipheral neuropathy

Identifiers

PMID40814516
PMCPMC12349835

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.