Evidence map›Paper›PMID 40814417›Full record

ReviewNeuro-oncology practice2025

Measures of physical functioning in adults with brain tumor associated with functional outcomes: A scoping review.

Tara S Davis, Emory Hsieh, Bennett A McIver, Kaitlynn Slattery, McKenzie C Kauss, Diane Cooper, Vivian A Guedes, Terri S Armstrong, Michelle L Wright

Abstract readReview
In one paragraph

Review in Neuro-oncology practice, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Tara S DavisNeuro-Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States.ORCID https://orcid.org/0000-0002-6293-3602
Emory HsiehNeuro-Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States.
Bennett A McIverNeuro-Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States.
Kaitlynn SlatteryNeuro-Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States.
McKenzie C KaussNeuro-Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States.
Diane CooperNational Institutes of Health Library, Office of Research Services National Institutes of Health, Bethesda, Maryland, United States.
Vivian A GuedesNeuro-Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States.
Terri S ArmstrongNeuro-Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States.ORCID https://orcid.org/0000-0002-2414-0492
Michelle L WrightNeuro-Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neuro-oncology researchers and clinicians rely mostly on subjective measures to evaluate physical functioning (PF) and predict survival in primary brain tumor (PBT) patients. Exploring alternative clinical outcome assessment (COA) measures may identify more objective measures that better quantify PF in PBT patients. A scoping review was conducted to identify studies related to PF measures used in PBT patients. Using the PRISMA-SCRA guideline 3 databases (PubMed, Web of Science, and Cochrane Library) were searched on January 25, 2024. Reviewers performed an independent review of titles, abstracts, and full text using covidence systematic review software and a standardized Microsoft Excel form for extracting data. 1093 publications were identified; 49 studies met eligibility criteria. Studies used a variety of PF measures evaluated at different time points, ranging from preintervention to 3 years or more postintervention. 39 PF COA measures were identified. Of the 39, 3 clinician-reported measures (ClinRO) [KPS, ECOG, and FIM] are validated for PBT. Many measures found are standardized for other neurological diseases including performance (PerfO) and patient-reported outcome (PRO) measures. Validation of additional COA types (PerfO and PRO) that are complementary to the ClinRO measures already validated for the PBT population should be established. Measures of interest should include the evaluation of walking due to its clinical relevance and indication for overall PF.

Indexed as

brain neoplasmsfunctional statuspatient outcome assessment

Identifiers

PMID40814417
PMCPMC12349772

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.