ArticleAnnals of pediatric cardiology
Determining the optimal timing for Tetralogy of Fallot management: A meta-analysis of neonatal vs postneonatal repairs.
Article in Annals of pediatric cardiology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
5 citing papers in PubMed.
- Risk factors and a predictive model for delayed extubation in children undergoing primary repair of tetralogy of Fallot: a retrospective cohort study with rigorous methodological validation.Frontiers in pediatrics · 2026Article
- Critique on "determining the optimal timing for tetralogy of Fallot management: A meta-analysis of neonatal versus postneonatal repairs".Annals of pediatric cardiologyArticle
- Response to the commentary on "determining the optimal timing for tetralogy of Fallot management: A meta-analysis of neonatal versus postneonatal repairs".Annals of pediatric cardiologyArticle
- Comment on: Determining the optimal timing for tetralogy of Fallot management: A meta-analysis of neonatal versus postneonatal repairs.Annals of pediatric cardiologyArticle
- Surgical outcomes of repair for tetralogy of Fallot with a previous right ventricular outflow tract stent.Annals of pediatric cardiologyArticle
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Tetralogy of Fallot (TOF), the most prevalent cyanotic congenital heart anomaly, impacts around 3.9 in 10,000 live births. Repair aims to address intracardiac shunting and right ventricular outflow tract obstruction. Despite successful historical surgeries, the optimal timing for repair remains debated. Objective: The aim of the study was to provide an updated comparison of the TOF repair timing (neonatal vs. postneonatal periods) based on post- and perioperative outcomes. Methods: A literature search was conducted across PubMed, Scopus, EBSCO, Science Direct, and Epistemonikos. Quality assessment was performed using the Risk of Bias in Non-Randomized Studies of Interventions, whereas the outcomes were analyzed using RevMan 5.4. Results: Nineteen studies comprising 28,968 patients were included in the study. All studies were classified as high-quality. The neonatal repair exhibited longer intensive care unit (ICU) stays (standard mean differences [SMD] 1.58; 95% confidence interval [CI] 1.04-2.12; Conclusion: Complete repair during the post-neonatal period yielded better postoperative outcomes, shorter hospital stays, ICU stays, and ventilation time.PROSPERO registration: CRD42024503630.
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