Evidence map›Paper›PMID 40814305›Full record

ArticleCurrent addiction reports2025

Use of Illegally Manufactured Fentanyl in the United States: Current Trends.

Nicole D Fitzgerald, Joseph J Palamar, Linda B Cottler

Abstract read
In one paragraph

Article in Current addiction reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Nicole D FitzgeraldDepartment of Epidemiology, Columbia Mailman School of Public Health, 722 West 168th Street, New York 10032, NY, USA.
Joseph J PalamarDepartment of Population Health, NYU Grossman School of Medicine, New York, NY, USA.
Linda B CottlerDepartment of Epidemiology, College of Public Health and Health Professions, College of Medicine, University of Florida, Gainesville, FL, USA.

Funding

National Drug Early Warning System (NDEWS) COVID-19 SupplementU01DA051126 · NIDA · UNIVERSITY OF FLORIDA · PI Linda B. Cottler, Joseph J Palamar · 2020 to 2026
$6.3M
Substance Abuse Epidemiology Training Program (SAETP) at Columbia UniversityT32DA031099 · NIDA · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI DEBORAH S HASIN, Silvia Saboia Martins · 2012 to 2026
$6.1M
New psychoactive substance exposure among NYC nightclub and festival attendeesR01DA057289 · NIDA · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI Joseph J Palamar · 2023 to 2026
$2.7M
NIDA NIH HHS R01 DA057289NIDA NIH HHS T32 DA031099NIDA NIH HHS U01 DA051126
6 · The paper itself

Abstract

Purpose of Review: As the overdose crisis evolves, it is important to monitor fentanyl consumption patterns. This review provides an overview of recent findings regarding illegally manufactured fentanyl (IMF) availability, use, and associated harms in the US. Recent Findings: Availability of IMF has increased, especially in pill form, and the increasing adulteration of IMF with veterinary tranquilizers such as xylazine complicates overdose response. Prevalence in the general population based on self-reported IMF use is rare, and likely underestimated. Transitions from injection to smoking have been documented in recent years, particularly in the western US. Fentanyl-stimulant polysubstance use has also been observed increasingly among IMF-related overdose deaths. Summary: Shifts in routes of administration, availability of counterfeit pills containing fentanyl, and common adulterants add complexity to the landscape of IMF use and related harms. Additional data is needed for monitoring changes in consumption patterns to inform prevention and harm reduction efforts.

Indexed as

EpidemiologyIllegally manufactured fentanylOpioidsOverdoseXylazine

Identifiers

PMID40814305
PMCPMC12346689

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.