Evidence map›Paper›PMID 40814099›Full record

Observational studyBMC public health2025

Prevalence of lead poisoning among artisanal gold miners in French Guiana in 2022: a multicenter cross-sectional observational survey.

Maylis Douine, Virgile Korsec, Alice Sanna, Lorraine Plessis, Teddy Bardon, Antoine Adenis, Mathieu Nacher, Martha Suarez-Mutis, Stephen Vreden, Olivier Mathieu and 1 more

Registry-linked trialAbstract readMulticenter StudyObservational Study
In one paragraph

Observational study in BMC public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05540470 (Radical CUREfor MAlaria Among Highly Mobile and Hard-to-reach Populations in the Guyanese Shield), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05540470 nacompletednot on this map

Radical CUREfor MAlaria Among Highly Mobile and Hard-to-reach Populations in the Guyanese Shield

TypeinterventionalSponsorCentre Hospitalier de CayenneRan2022 to 2025Enrolled1,991ConditionsMalaria, VivaxArmsPART, Malakit, CROSS-SECTIONAL PRE- AND POST-INTERVENTION SURVEYS, QUALITATIVE STUDY
3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Maylis DouineCentre d'Investigation Clinique Antilles-Guyane Inserm 1424, Département Recherche-Innovation-Santé publique, Centre Hospitalier Universitaire de Guyane, Cayenne, French Guiana, France. mdouine@yahoo.fr.
Virgile KorsecCentre d'Investigation Clinique Antilles-Guyane Inserm 1424, Département Recherche-Innovation-Santé publique, Centre Hospitalier Universitaire de Guyane, Cayenne, French Guiana, France.
Alice SannaCentre d'Investigation Clinique Antilles-Guyane Inserm 1424, Département Recherche-Innovation-Santé publique, Centre Hospitalier Universitaire de Guyane, Cayenne, French Guiana, France.
Lorraine PlessisCentre d'Investigation Clinique Antilles-Guyane Inserm 1424, Département Recherche-Innovation-Santé publique, Centre Hospitalier Universitaire de Guyane, Cayenne, French Guiana, France.
Teddy BardonCentre d'Investigation Clinique Antilles-Guyane Inserm 1424, Département Recherche-Innovation-Santé publique, Centre Hospitalier Universitaire de Guyane, Cayenne, French Guiana, France.
Antoine AdenisCentre d'Investigation Clinique Antilles-Guyane Inserm 1424, Département Recherche-Innovation-Santé publique, Centre Hospitalier Universitaire de Guyane, Cayenne, French Guiana, France.
Mathieu NacherCentre d'Investigation Clinique Antilles-Guyane Inserm 1424, Département Recherche-Innovation-Santé publique, Centre Hospitalier Universitaire de Guyane, Cayenne, French Guiana, France.
Martha Suarez-MutisLaboratory of Parasitic Diseases, Institute Oswaldo Cruz/Fiocruz, Rio de Janeiro, Brazil.
Stephen VredenFoundation for the Advancement of Scientific Research, Paramaribo, Suriname.
Olivier MathieuService de Pharmacologie Médicale et Toxicologie, Centre hospitalier universitaire de Montpellier, et Equipe ContEm - UMR 5151 Hydrosciences, Université de Montpellier, Montpellier, France.
Yann LambertCentre d'Investigation Clinique Antilles-Guyane Inserm 1424, Département Recherche-Innovation-Santé publique, Centre Hospitalier Universitaire de Guyane, Cayenne, French Guiana, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLead poisoning is a significant public health issue globally. In French Guiana, a French overseas territory in South America, several studies have reported widespread lead exposure in the local population. However, the associated risk factors remain insufficiently understood. People working in informal gold mining share part of their lifestyle with French Guianese communities. The objectives of this study were to describe the prevalence of lead poisoning and to identify associated risk factors among gold mine workers in 2022.

methodsThis cross-sectional descriptive study was based on data collected by questionnaire and blood sampling. Persons working in informal gold mines were enrolled on the logistic rear bases on the Surinamese and Brazilian sites of the bordering rivers. Blood lead levels were measured on dry blood spots (50 µl). Using a threshold of 100 µg/L, single and multiple regressions were used to assess the associated factors.

resultsAmong the 526 persons included, the median age was 38 years and 73.5% were men. The prevalence of lead poisoning was 44.7% (95%CI = 40.4%-49.0%). The factors associated with a BLL over 100 µg/L were: amount of time spent in gold mining (OR = 1.31 [1.09-1.58]), occupation with mud exposure (OR = 1.67 [1.13-2.48]), working in the Southwestern region (OR = 2.09 [1.34-3.27]) and consuming game (OR = 1.58 [1.06-2.36]).

conclusionThe people working on gold mining sites are highly exposed to lead poisoning. The risk factors are suggestive of environmental contamination and differ from those suspected in the population of French Guiana.

trial registrationThis study is registered on ClinicalTrials.gov under the identifier NCT05540470 (registered on September 12, 2022).

Indexed as

GoldLead PoisoningMinersMiningOccupational ExposureAdultCross-Sectional StudiesFemaleFrench GuianaHumansMaleMiddle AgedPrevalenceRisk FactorsSurveys and QuestionnairesGoldAmazonFrench guianaGold miningHeavy metalLead poisoningPoisoning

Identifiers

PMID40814099
PMCPMC12351931

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.