ArticleBMC cardiovascular disorders2025
Real-world analysis of characteristics and guideline adherence of antiplatelet drugs prescriptions among patients with coronary artery disease and its comorbidities: a cross-sectional study.
Article in BMC cardiovascular disorders, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
objectivesTo identify the characteristics of antiplatelet drug (APD) prescriptions based on a regional large-scale outpatient database in Shanghai, China, and to compare the practical usage of APDs with the respective clinical guidelines for patients with coronary artery disease (CAD) in China.
methodsOutpatient electronic healthcare records were extracted from 20 medical institutions in Shanghai from January 2020 to October 2021. Outpatient APD prescriptions among CAD patients and their comorbidity status were analyzed with the χ
resultsOf 1,532,972 outpatient visits, only 284,400 (18.55%) involved APDs. APD were more likely to be utilized in patients with recent ACS (27.60%) (χ
conclusionThe proportion of APD prescriptions for CAD outpatients was lower than expected. The rationality analysis revealed that both CCS and recent ACS patients showed suboptimal guideline adherence in real-world APD prescriptions, especially for patients with comorbid reflux esophagitis. The gap indicated that real-world prescription activity for these diseases should receive more attention.
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