Evidence map›Paper›PMID 40814082›Full record

ArticleBMC cardiovascular disorders2025

Real-world analysis of characteristics and guideline adherence of antiplatelet drugs prescriptions among patients with coronary artery disease and its comorbidities: a cross-sectional study.

Ting Lu, Zhe Yang, Peipei Zhang, Haiyan Zhu, Qiao Chu, Limei Jing, Wanju Sun, Jianwei Shi

Abstract readMulticenter StudyComparative Study
In one paragraph

Article in BMC cardiovascular disorders, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Ting Lu *Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China.
Zhe Yang *Shanghai YangZhi Rehabilitation Hospital, School of Medicine, Tongji University, Shanghai, 201619, China.
Peipei ZhangShanghai Jia Ding District An'ting Hospital, Shanghai, 201805, China.
Haiyan ZhuShanghai Pudong New Area People's Hospital, 490 Chuanhuan South RD, Shanghai, 201299, China.
Qiao ChuSchool of Public Health, Shanghai Jiaotong University School of Medicine, 227 Chongqing South RD, Shanghai, 200025, China.
Limei JingSchool of Public Health, Shanghai Jiaotong University School of Medicine, 227 Chongqing South RD, Shanghai, 200025, China.
Wanju SunShanghai Pudong New Area People's Hospital, 490 Chuanhuan South RD, Shanghai, 201299, China. sunwanju2021@163.com.
Jianwei ShiSchool of Public Health, Shanghai Jiaotong University School of Medicine, 227 Chongqing South RD, Shanghai, 200025, China. shijianwei_amy@126.com.

Funding

Natural Science Foundation of Shanghai Municipality 71603182the Family Planning Health Scientific Research Project of Shanghai Pudong New Area Health Commission PW2019D-14the Soft Science Project of Shanghai Science and Technology Commission 24692113600
6 · The paper itself

Abstract

objectivesTo identify the characteristics of antiplatelet drug (APD) prescriptions based on a regional large-scale outpatient database in Shanghai, China, and to compare the practical usage of APDs with the respective clinical guidelines for patients with coronary artery disease (CAD) in China.

methodsOutpatient electronic healthcare records were extracted from 20 medical institutions in Shanghai from January 2020 to October 2021. Outpatient APD prescriptions among CAD patients and their comorbidity status were analyzed with the χ

resultsOf 1,532,972 outpatient visits, only 284,400 (18.55%) involved APDs. APD were more likely to be utilized in patients with recent ACS (27.60%) (χ

conclusionThe proportion of APD prescriptions for CAD outpatients was lower than expected. The rationality analysis revealed that both CCS and recent ACS patients showed suboptimal guideline adherence in real-world APD prescriptions, especially for patients with comorbid reflux esophagitis. The gap indicated that real-world prescription activity for these diseases should receive more attention.

Indexed as

Coronary Artery DiseaseGuideline AdherencePlatelet Aggregation InhibitorsPractice Patterns, Physicians'AgedChinaComorbidityCross-Sectional StudiesDatabases, FactualDrug PrescriptionsFemaleHumansMaleMiddle AgedPractice Guidelines as TopicRetrospective StudiesPlatelet Aggregation InhibitorsAntiplatelet drugComorbidityCoronary artery diseaseRationality

Identifiers

PMID40814082
PMCPMC12351791

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.