Evidence map›Paper›PMID 40814042›Full record

ArticleBMC public health2025

Doxycycline post-exposure prophylaxis in China: current utilized situation among men who have sex with men in a cross-sectional online survey from two cites.

Xu Zhang, Fang-Zhi Du, Xiao-Li Zheng, Rui-Li Zhang, Qian-Qiu Wang

Abstract read
In one paragraph

Article in BMC public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Xu ZhangHospital for Skin Diseases, Institute of Dermatology, Chinese Academy of Medical Sciences & Peking Union Medical College, Nanjing, 210042, China.
Fang-Zhi DuHospital for Skin Diseases, Institute of Dermatology, Chinese Academy of Medical Sciences & Peking Union Medical College, Nanjing, 210042, China.
Xiao-Li ZhengHospital for Skin Diseases, Institute of Dermatology, Chinese Academy of Medical Sciences & Peking Union Medical College, Nanjing, 210042, China.
Rui-Li ZhangDepartment of Dermatology, The Second Affiliated Hospital of Nanjing Medical University, Nanjing, 210011, China.
Qian-Qiu WangHospital for Skin Diseases, Institute of Dermatology, Chinese Academy of Medical Sciences & Peking Union Medical College, Nanjing, 210042, China. wangqianqiunj@126.com.

Funding

CAMS Innovation Fund for Medical Sciences CIFMS-2021-I2M-1-001
6 · The paper itself

Abstract

backgroundDoxycycline post-exposure prophylaxis (Doxy-PEP) represents an emerging strategy for STI prevention. Self-administered use of Doxy-PEP has been empirically observed among men who have sex with men (MSM) in some countries, while little is known about current use of it in the Chinese population.

methodsAn online survey was conducted among MSM in two cities in China. We detected the current utilized situation of Doxy-PEP with descriptive statistics and constructed χ2 or Fisher’s exact tests for factors associated with self-administered Doxy-PEP use.

resultsThree hundred thirteen individuals returned the results of the questionnaire. Most of them under 35 years of age (79.55%), had college degrees (70.61%) and worked in private institutions (36.42%) or were freelancers (24.28%). 34.2% had heard of Doxy-PEP and 12.1% had used it, while 8.31% were self-initiated users. Doxy-PEP self-initiated use behavior was found to be associated with multiple sexual partners (P = 0.013) and HIV PrEP/PEP experience (P < 0.001). 89.47% of the Doxy-PEP users showed interest in promoting it to others in the future.

conclusionSelf-initiated use of Doxy-PEP is prevalent among Chinese MSM, and should be taken into consideration for future public health intervention programs aimed at promoting and implementing Doxy-PEP in China.

Indexed as

Anti-Bacterial AgentsDoxycyclineHomosexuality, MalePost-Exposure ProphylaxisSexually Transmitted DiseasesAdolescentAdultChinaCross-Sectional StudiesHumansMaleMiddle AgedSurveys and QuestionnairesYoung AdultAnti-Bacterial AgentsDoxycyclineCross-sectional surveyDoxycyclineMSMPost-exposure prophylaxisSyphilis

Identifiers

PMID40814042
PMCPMC12351837

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.