Evidence map›Paper›PMID 40814002›Full record

ReviewOne health outlook2025

Evaluation of guidelines on antimicrobials use in food-producing animals: a systematic review.

Jacinta Oliveira Pinho, Ana Isabel Plácido, Alexandra Monteiro, Rafaela Nogueira, Paula Alexandra Oliveira, Ana Claúdia Coelho, Adolfo Figueiras, Fátima Roque, Maria Teresa Herdeiro

Abstract readReview
In one paragraph

Review in One health outlook, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Characterization ofFrontiers in veterinary science · 2026
    Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jacinta Oliveira Pinho *Department of Medical Sciences, Institute of Biomedicine (iBiMED), University of Aveiro, Campus Universitário de Santiago, Agra do Crasto, Aveiro, 3810-193, Portugal.
Ana Isabel Plácido *BRIDGES - Biotechnology Research, Innovation and Design for Health Products, Polytechnic University of Guarda, Avenida Dr. Francisco Sá Carneiro, N. 50, Guarda, 6300-559, Portugal.
Alexandra MonteiroBRIDGES - Biotechnology Research, Innovation and Design for Health Products, Polytechnic University of Guarda, Avenida Dr. Francisco Sá Carneiro, N. 50, Guarda, 6300-559, Portugal.
Rafaela NogueiraCentre for the Research and Technology of Agro-Environmental and Biological Sciences (CITAB), University of Trás-Os-Montes and Alto Douro (UTAD), Vila Real, Portugal.
Paula Alexandra OliveiraCentre for the Research and Technology of Agro-Environmental and Biological Sciences (CITAB), University of Trás-Os-Montes and Alto Douro (UTAD), Vila Real, Portugal.
Ana Claúdia CoelhoAnimal and Veterinary Research Centre (CECAV), Department of Veterinary Sciences, University of Trás-Os-Montes and Alto Douro (UTAD), Vila Real, Portugal.
Adolfo FigueirasDepartment of Preventive Medicine and Public Health, University of Santiago de Compostela; Health Research Institute of Santiago de Compostela (IDIS), Santiago de Compostela, Spain.
Fátima RoqueBRIDGES - Biotechnology Research, Innovation and Design for Health Products, Polytechnic University of Guarda, Avenida Dr. Francisco Sá Carneiro, N. 50, Guarda, 6300-559, Portugal.
Maria Teresa HerdeiroDepartment of Medical Sciences, Institute of Biomedicine (iBiMED), University of Aveiro, Campus Universitário de Santiago, Agra do Crasto, Aveiro, 3810-193, Portugal. teresaherdeiro@ua.pt.

Funding

COMPUTER AIDED ANALYSIS OF ELECTROCARDIOGRAPHYZ01CT000002 · CIT · COMPUTER RESEARCH AND TECHNOLOGY · PI BAILEY, JAMES J. · 1985 to 2003
–
Fundação para a Ciência e a Tecnologia 2022.04568.PTDCFundação para a Ciência e a Tecnologia CEECINST/00093/2021/CP2815/CT0002Intramural NIH HHS Z01 CT000002
6 · The paper itself

Abstract

backgroundAntimicrobial resistance (AMR) is a global public health problem due to misuse/overuse of antimicrobials. The interplay between humans, animals, and the environment requires a One Health approach for effective AMR control. We focused this research on antimicrobial use in food-producing animals (bovine, caprine, equine, ovine, and swine) to assess the compliance of Organisation for Economic Co-operation and Development (OECD) countries (members, partners, and candidates) with international guidelines: Codex Alimentarius: Code of Practice to Minimize and Contain Foodborne Antimicrobial Resistance, and the Terrestrial Animal Health Code.

methodsFor this systematic review (PROSPERO CRD42024535461), between February 1 and June 30 of 2024, guidelines were searched on: governmental websites associated with health and veterinary sectors, veterinary organizations specified by the government or included in the country's National Action Plan for AMR, and the global repository of available guidelines for responsible use of antimicrobials in animal health. Three researchers performed data extraction and AGREE II appraisal was conducted by two researchers.

resultsOf the 49 OECD countries, 37 presented guidelines (n = 82) for responsible antimicrobial use in the analyzed species, with bovine and swine being the most represented. The highest number of published guidelines was observed between 2017-2020. The number of clinical and non-clinical guidelines were 43 and 37, respectively, emphasizing the need for veterinarian-directed recommendations.

conclusionsThe AMR challenge, the interdependence of countries, and the trade of animal-derived products should encourage national initiatives to develop and implement guidelines for the judicious use of antimicrobials in animal production. Due to OECD countries' disparities in terms of culture, internal policies, attitudes and perceptions about AMR, and financial resources, this process needs to be gradual and tailored for each case. Therefore, communication and collaboration between countries and stakeholders are essential.

Indexed as

Antimicrobial resistanceFood-producing animalsOECD-related countriesOne Health approachVeterinary guidelines

Identifiers

PMID40814002
PMCPMC12351981

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.