Evidence map›Paper›PMID 40813751›Full record

SynthesisDevelopmental medicine and child neurology2025

Application of the Gross Motor Function Measure in children with conditions other than cerebral palsy: A systematic review.

Hirokazu Abe, Shuhei Higashi, Nobuaki Himuro

Abstract readSystematic Review
In one paragraph

Synthesis in Developmental medicine and child neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Article
  7. Early Motor Development and Rehabilitation Outcomes in Apert Syndrome: Gross Motor Function Measures-Case Report.Pathophysiology : the official journal of the International Society for Pathophysiology · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Hirokazu AbeDepartment of Health Care and Child Development, Saitama Children's Medical Center, Saitama, Japan.ORCID 0000-0003-1615-9959
Shuhei HigashiDepartment of Physical Therapy, Kitakyushu Children's Rehabilitation Center, Kitakyushu, Japan.
Nobuaki HimuroDepartment of Public Health, School of Medicine, Sapporo Medical University, Sapporo, Japan.ORCID 0000-0003-2609-0510

Funding

Japan Society for the Promotion of Science JP 21K11315
6 · The paper itself

Abstract

aimTo investigate the application and evaluate the measurement properties of the Gross Motor Function Measure (GMFM) in children with conditions other than cerebral palsy (CP).

methodA systematic review was conducted using five electronic databases to identify studies that used the GMFM in children with conditions other than CP. Methodological quality and measurement properties were evaluated using established standards for assessing outcome measures.

resultsWe identified 210 studies across various paediatric conditions. Measurement property studies examined eight conditions: acquired brain injury, spinal muscular atrophy, Fukuyama congenital muscular dystrophy, Down syndrome, osteogenesis imperfecta, acute lymphoblastic leukaemia (ALL), leukodystrophy, and Pompe disease. Evidence quality was generally low to very low owing to small sample sizes and methodological limitations. Reliability showed sufficient ratings across most conditions. Content validity was examined only for ALL and demonstrated sufficient ratings. Responsiveness and construct validity showed variable results across conditions. Clinical application analysis revealed inadequate methodological reporting and widespread use without appropriate validation.

interpretationGMFM validation for conditions other than CP remains insufficient despite widespread use. Content validity verification and enhanced methodological rigor are critically needed. Clinicians should interpret results cautiously until robust validation is established.

Indexed as

Disability EvaluationMotor SkillsCerebral PalsyChildHumansReproducibility of Results

Identifiers

PMID40813751
PMCPMC12521613

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.