Evidence map›Paper›PMID 40813723›Full record

ArticleMilitary Medical Research2025

Sudden cardiac arrest mortality in China: temporal trends and risk factors.

Yang Yu, Jie Wang, Ji-Fei Wang, Jiang-Mei Liu, Xiao-Jie Liu, Yu-Chen Gao, Sudena Wang, Yao Ding, Yao Lu, Mai-Geng Zhou and 2 more

Abstract read
In one paragraph

Article in Military Medical Research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Trial
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Yang Yu *Department of Anesthesiology, Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100037, China.
Jie Wang *Clinical Research Center, the Third Xiangya Hospital, Central South University, Changsha, 410013, China.
Ji-Fei Wang *National Center for Chronic and Noncommunicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, 100050, China.
Jiang-Mei LiuNational Center for Chronic and Noncommunicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, 100050, China.
Xiao-Jie LiuDepartment of Anesthesiology, Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100037, China.
Yu-Chen GaoDepartment of Anesthesiology, Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100037, China.
Sudena WangDepartment of Anesthesiology, Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100037, China.
Yao DingDepartment of Anesthesiology, Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100037, China.
Yao LuClinical Research Center, the Third Xiangya Hospital, Central South University, Changsha, 410013, China. luyao0719@163.com.
Mai-Geng ZhouNational Center for Chronic and Noncommunicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, 100050, China. zhoumaigeng@ncncd.chinacdc.cn.
Marie NgYong Loo Lin School of Medicine, National University of Singapore, Singapore, 117599, Singapore. marieng@nus.edu.sg.
Hu-Shan AoDepartment of Anesthesiology, Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100037, China. aohushan@126.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSudden cardiac death (SCD) accounts for more than half of all sudden death cases, posing a significant health burden in China. However, epidemiological data on SCD are scarce due to the lack of a central data registry and the heterogeneity of case definitions. This study aims to provide reliable estimates of the incidence and risk factors of SCD in China at the national and regional levels from 2013 to 2021, as well as the current status of prevention.

methodsThe multi-cause mortality data from 2013 to 2021 were obtained from the National Mortality Surveillance System of China. Deaths related to cardiac arrest were identified. Crude and age-standardized mortality rates were calculated by time, and region. Joint point regression was applied to identify significant changes during the study period. Subgroup analyses and multilevel negative binomial analysis were performed to understand the SCD risk factors. The first-line prevention measures and their current implementation in China and developed countries were also determined from published articles.

resultsFrom 2013 to 2021, the crude mortality rate of sudden cardiac arrest increased markedly from 8.36 deaths per 100,000 population in 2013 to 18.59 deaths per 100,000 population in 2021. There were considerable differences among regions. Subgroup analysis and negative binomial regression results indicated that males and the elderly were at higher risk of SCD. SCD may be associated with poor medical conditions. More than half of SCDs occurred outside hospitals, and approximately 60% of SCDs were related to ischemic heart disease as the underlying cause. Currently, developed countries have widely adopted primary prevention and emergency treatment measures; however, the utilization rate of such measures in China is relatively low and should be improved.

conclusionsWith the continuous rise in the prevalence of cardiovascular diseases and their related risk factors in China, the burden of SCD is expected to increase. In addition to strengthening the clinical pathways for sudden cardiac arrest cases in pre-hospital and hospital settings, it is also necessary to enhance public awareness, knowledge and first-line practical training through large-scale policies for governmental and community-based projects.

Indexed as

Death, Sudden, CardiacAdolescentAdultAgedAged, 80 and overChinaFemaleHumansIncidenceMaleMiddle AgedMortalityRisk FactorsAge-standardized mortality rates (ASMR)Mortality rateNational mortality surveillance system (NMSS)Sudden cardiac death (SCD)

Identifiers

PMID40813723
PMCPMC12355832

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.