Evidence map›Paper›PMID 40813714›Full record

ArticleMalaria journal2025

"We witnessed medicines help our children, then we became proud": experiences and acceptability of seasonal malaria chemoprevention in Aweil, South Sudan.

Francis Okot, Maria Suau Sans, Erica Viganò, Abubaker Rom, Denis Mubiru, Kevin Baker, Jamshed Khan, Ahmed Julla

Abstract read
In one paragraph

Article in Malaria journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Francis OkotMalaria Consortium, Juba, South Sudan. f.lokang.57@malariaconsortium.org.
Maria Suau SansMalaria Consortium, London, UK.
Erica ViganòMalaria Consortium, London, UK.
Abubaker RomMalaria Consortium, Juba, South Sudan.
Denis MubiruMalaria Consortium, Juba, South Sudan.
Kevin BakerMalaria Consortium, London, UK.
Jamshed KhanMalaria Consortium, Juba, South Sudan.
Ahmed JullaNational Ministry of Health, Juba, South Sudan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMalaria remains a significant public health concern, particularly in resource-constrained settings and regions affected by ongoing humanitarian crises, such as Northen Bahr el Ghazal in South Sudan. For successful implementation and uptake of malaria interventions, it is important to understand community perceptions in these contexts. Therefore, we present the findings of the qualitative study examining the feasibility of implementing seasonal malaria chemoprevention (SMC) and acceptability of the intervention by the community in this complex setting.

methodsFive monthly cycles of SMC with sulfadoxine-pyrimethamine plus amodiaquine were distributed to children aged 3-59 months in Aweil South county, in Northen Bahr el Gazal. Following the completion of the fifth SMC cycle a qualitative study was conducted to understand perspective on SMC acceptability. Data were collected through key informant interviews with community leaders and other stakeholders at the county and national level and focus group discussions with caregivers of children aged 3-59 months and Boma Health Workers. Data were coded using inductive and deductive approaches.

resultsAmong the 97 participants, there was high acceptability of SMC. Factors reported that positively influenced acceptability included the perceived effectiveness of SMC in preventing malaria, the door-to-door delivery strategy and the use of trusted Boma Health Workers to deliver SMC. However, challenges reported as affecting feasibility included environmental barriers, inadequate remuneration for Boma Health Workers, and difficulties reaching all eligible children. Stakeholders also expressed a desire for SMC continuation and expansion, emphasizing the positive economic impact.

conclusionThis study provides crucial insights into factors influencing acceptability of SMC in a fragile setting, which can be used to refine community engagement strategies for SMC and generate guidelines for optimizing SMC in similar challenging contexts.

Indexed as

AmodiaquineAntimalarialsChemopreventionMalariaPatient Acceptance of Health CarePyrimethamineSulfadoxineChild, PreschoolDrug CombinationsFemaleHumansInfantMaleSeasonsSouth SudanAmodiaquineAntimalarialsDrug Combinationsfanasil, pyrimethamine drug combinationPyrimethamineSulfadoxineAcceptabilityCommunity healthComplex operating environmentMalariaSeasonal malaria chemopreventionSouth Sudan

Identifiers

PMID40813714
PMCPMC12355734

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LicenceCC BY-NC-ND
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.