Evidence map›Paper›PMID 40813707›Full record

ArticleJournal of experimental & clinical cancer research : CR2025

HAS1

Wanyong Jin, Qiuya Yu, Liyuan Yu, Ting Zhou, Xiren Wang, Wanqiu Lu, Xiaoxin Zhang, Liang Ding, Qingang Hu, Yanhong Ni

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of experimental & clinical cancer research : CR, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Wanyong JinCentral Laboratory of Stomatology, Nanjing Stomatological Hospital, Affiliated Hospital of Medical School, Institute of Stomatology, Nanjing University, No. 30 Zhongyang Road, Nanjing, 210008, China.
Qiuya YuCentral Laboratory of Stomatology, Nanjing Stomatological Hospital, Affiliated Hospital of Medical School, Institute of Stomatology, Nanjing University, No. 30 Zhongyang Road, Nanjing, 210008, China.
Liyuan YuCentral Laboratory of Stomatology, Nanjing Stomatological Hospital, Affiliated Hospital of Medical School, Institute of Stomatology, Nanjing University, No. 30 Zhongyang Road, Nanjing, 210008, China.
Ting ZhouCentral Laboratory of Stomatology, Nanjing Stomatological Hospital, Affiliated Hospital of Medical School, Institute of Stomatology, Nanjing University, No. 30 Zhongyang Road, Nanjing, 210008, China.
Xiren WangCentral Laboratory of Stomatology, Nanjing Stomatological Hospital, Affiliated Hospital of Medical School, Institute of Stomatology, Nanjing University, No. 30 Zhongyang Road, Nanjing, 210008, China.
Wanqiu LuSchool of Biopharmacy, China Pharmaceutical University, Nanjing, Jiangsu, China.
Xiaoxin ZhangCentral Laboratory of Stomatology, Nanjing Stomatological Hospital, Affiliated Hospital of Medical School, Institute of Stomatology, Nanjing University, No. 30 Zhongyang Road, Nanjing, 210008, China.
Liang DingCentral Laboratory of Stomatology, Nanjing Stomatological Hospital, Affiliated Hospital of Medical School, Institute of Stomatology, Nanjing University, No. 30 Zhongyang Road, Nanjing, 210008, China.
Qingang HuCentral Laboratory of Stomatology, Nanjing Stomatological Hospital, Affiliated Hospital of Medical School, Institute of Stomatology, Nanjing University, No. 30 Zhongyang Road, Nanjing, 210008, China. qghu@nju.edu.cn.
Yanhong NiCentral Laboratory of Stomatology, Nanjing Stomatological Hospital, Affiliated Hospital of Medical School, Institute of Stomatology, Nanjing University, No. 30 Zhongyang Road, Nanjing, 210008, China. Yanhong.Ni@nju.edu.cn.

Funding

Cultivation Program for Junior Talents of Nanjing Stomatological School, Medical School of Nanjing University 0222R216Nanjing Medical Science and Technique Development Foundation ZDX22001Nanjing Medical Science and Technology Development Foundation, Nanjing Municipal Health Commission YKK20151National Outstanding Youth Science Fund Project of National Natural Science Foundation of China 82173159
6 · The paper itself

Abstract

backgroundAlthough tumor cell heterogeneity between the tumor center (TC) and invasion front (IF) of oral squamous cell carcinoma (OSCC) is well documented, the morphological, molecular, and functional characteristics of cancer-associated fibroblasts (CAFs) in these regions remain poorly understood.

methodsWe examined hematoxylin and eosin (H&E)-stained OSCC sections to assess CAF morphology and correlation with patient prognosis. We then isolated paired CAFs from the tumor center (CAF

resultsCompared to CAF

conclusionCAF

Indexed as

Cancer-Associated FibroblastsCarcinoma, Squamous CellExtracellular MatrixHyaluronan SynthasesMouth NeoplasmsCell Line, TumorFemaleGene Expression Regulation, NeoplasticHumansMaleMiddle AgedNeoplasm InvasivenessPrognosisHAS1 protein, humanHyaluronan SynthasesCancer associated fibroblastExtracellular matrix remodelingInvasion frontOral squamous cell carcinoma

Identifiers

PMID40813707
PMCPMC12351772

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.