Evidence map›Paper›PMID 40813652›Full record

Trial reportBMC pregnancy and childbirth2025

Optimal group and individual prenatal care visit patterns and preterm birth.

Moonseong Heo, Jessica L Britt, Lu Zhang, Emily A Doherty, Amy H Crockett

Registry-linked trialAbstract readMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in BMC pregnancy and childbirth, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02640638 (Reducing Disparities in Birth Outcomes), which is not on this map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02640638 nacompletednot on this map

Reducing Disparities in Birth Outcomes: a Randomized Controlled Trial of CenteringPregnancy

TypeinterventionalSponsorClemson UniversityRan2016 to 2021Enrolled2,350ConditionsPregnancy, Preterm BirthArmsCenteringPregnancy
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Moonseong HeoDepartment of Public Health Sciences, College of Behavioral, Social and Health Sciences, Clemson University, 505 Edwards Hall, Clemson, SC, 29634, USA. mheo@clemson.edu.
Jessica L BrittDepartment of Obstetrics and Gynecology, Prisma Health, Greenville, SC, USA.
Lu ZhangDepartment of Public Health Sciences, College of Behavioral, Social and Health Sciences, Clemson University, 505 Edwards Hall, Clemson, SC, 29634, USA.
Emily A DohertyDepartment of Rural Health, Oklahoma State University Center for Health Sciences, Tulsa, OK, USA.
Amy H CrockettDepartment of Obstetrics and Gynecology, Prisma Health, Greenville, SC, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundChanges have recently been proposed to both the visit frequency and setting for delivery of prenatal care, including decreasing frequency of scheduled visits or using group visits or virtual visits. The impacts of participant engagement patterns with prenatal care on preterm birth (PTB) are not clearly understood. We aimed to characterize prenatal care visit patterns, examine their associations with PTB, and provide optimal cutoffs for care patterns.

methodsThis study is a secondary analysis of prenatal care visit data obtained from the randomized CRADLE study that tested the effects of group (GPNC) versus individual (IPNC) prenatal care on PTB. We analyzed prenatal care visit data from N = 1,989 medically low-risk pregnant women who had at least one prenatal care visit between study enrollment and gestational age (GA) week 37. Prenatal care visit patterns before GA week 37 were predictors, characterized in terms of the number of IPNC and GPNC visits, duration of care, total hours of care, GA week at last visit, minimum gap (> 21 vs. ≤ 21 days) between any or GPNC visits, and discontinuation before the third trimester. PTB was the study outcome, defined as delivery < 37 GA weeks. Simple and multivariable logistic regression models and ROC analysis were applied to test associations and determine optimal cutoff points.

resultsOverall, > 7 visits during pregnancy (OR = 0.58, 95%CI: 0.43–0.79, p < .001), > 3 visits in the third trimester (OR = 0.42, 95%CI: 0.30–0.57, p < .001), > 2.25 care hours during pregnancy (OR = 0.67, 95%CI: 0.49–0.92, p = .014), > 0.75 care hours during the third trimester (OR = 0.50, 95%CI: 0.37, 0.67, p < .001), and > 147 days in care (OR = 0.41, 95%CI: 0.30–0.56, p < .001) were all significantly associated with lower PTB rates. A minimum care gap of > 21 days was associated with higher PTB (aOR = 2.87, 95%CI: 1.76–4.69, p < .001) and discontinuation of care before the third trimester was the strongest correlate of PTB (aOR = 12.6, 95%CI: 6.5–24.5), p < .001) in terms of aOR compared to that of all the other pattern variables.

conclusionPatient engagement with prenatal care providers, including both duration and frequency, was associated with reduced risk of PTB. Any proposed revision to the schedule or frequency of prenatal care which decreases patient contact with healthcare providers may risk worsening birth outcomes. CLINICAL

trial registrationThis study was registered on December 20, 2015, at ClinicalTrials.gov ( www.clinicaltrials.gov , NCT02640638) with a title, A RCT of Centering Pregnancy on Birth Outcomes (CRADLE).

Indexed as

Office VisitsPremature BirthPrenatal CareAdultFemaleGestational AgeHumansLogistic ModelsPregnancyYoung AdultIndividual prenatal careOptimal prenatal carePregnant women group prenatal carePrenatal care patternsPreterm birth

Identifiers

PMID40813652
PMCPMC12351913

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.