Evidence map›Paper›PMID 40813555›Full record

ArticleChinese journal of integrative medicine2026

Anti-tumor Effects of Pollen Pini on Hepatocarcinoma SMMC-7721 Cells via Modulation of PI3K-Akt Signaling Pathway.

Yuan-Hong Chen, Wei-Xin Xu, Wen-Jun Yu, Chun-Fang Wang, Chun Guo, Yan-Hong Luo

Abstract read
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Article in Chinese journal of integrative medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yuan-Hong ChenDepartment of Pathogenic Biology and Immunology, Youjiang Medical University for Nationalities, Baise, Guangxi Zhuang Autonomous Region, 533000, China.
Wei-Xin XuDepartment of Pharmacy, Yancheng Clinical College of Xuzhou Medical University/the First People's Hospital of Yancheng, Yancheng, Jiangsu Province, 224001, China.
Wen-Jun YuDepartment of Mechanical Engineering and Materials Science, Duke University, Durham, NC, 27707, USA.
Chun-Fang WangCenter for Clinical Laboratory Diagnosis and Research, the Affiliated Hospital of Youjiang Medical University for Nationalities, Baise, Guangxi Zhuang Autonomous Region, 533000, China.
Chun GuoDepartment of Anatomy, School of Basic Medicine Science, Youjiang Medical University for Nationalities, Baise, Guangxi Zhuang Autonomous Region, 533000, China.
Yan-Hong LuoModern Industrial College of Biomedicine and Great Health, Youjiang Medical University for Nationalities, Baise, Guangxi Zhuang Autonomous Region, 533000, China. 00505@ymun.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo explore the effect of Pollen Pini (PP) on SMMC-7721 hepatoma cells.

methodsThe anti-proliferative effects of PP on SMMC-7721 cells were evaluated using cell counting kit-8 assay following 48 h treatment with concentrations ranging from 1.25 to 37.50 µg/µL Flow cytometry analysis at the half maximal inhibitory concentration (IC

resultsPP had an anti-tumor effect on SMMC-7721 cells in vitro, with the IC

conclusionPP has an anti-tumor effect on SMMC-7721 cells through the PI3K-Akt signaling pathway.

Indexed as

Antineoplastic AgentsCarcinoma, HepatocellularDrugs, Chinese HerbalLiver NeoplasmsPhosphatidylinositol 3-KinasesPollenProto-Oncogene Proteins c-aktSignal TransductionAnimalsApoptosisCell CycleCell Line, TumorCell ProliferationHumansMiceMice, Inbred BALB CAntineoplastic AgentsDrugs, Chinese HerbalPhosphatidylinositol 3-KinasesProto-Oncogene Proteins c-aktanti-tumor effectChinese medicinephosphoinositide-3 kinasePollen Piniprotein kinase BSMMC-7721

Identifiers

PMID40813555

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.