Evidence map›Paper›PMID 40813473›Full record

ArticleCardiovascular and interventional radiology2025

Glue Penetration Index Score for Use during Glue Prostate Artery Embolization.

Conrad von Stempel, Ganesh Vigneswaran, Mark Little, Alexis Quirantes, Ahmed Al-Nowfal, Shian Patel, David Beckett, Romaric Loffroy, Clare Bent

Abstract readMulticenter Study
PubMed Publisher
In one paragraph

Article in Cardiovascular and interventional radiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Conrad von StempelDepartment of Imaging, UCLH, London, UK.
Ganesh VigneswaranUniversity of Southampton, Southampton, UK.
Mark LittleUniversity Department of Radiology, Royal Berkshire NHS Foundation Trust, Reading, UK.
Alexis QuirantesDepartment of Vascular and Interventional Radiology, François-Mitterrand University Hospital, Dijon, France.
Ahmed Al-NowfalDepartment of Imaging, UCLH, London, UK.
Shian PatelDepartment of Interventional Radiology, University Hospitals Dorset, Castle Lane East, Bournemouth, BH7 7DW, UK.
David BeckettDepartment of Interventional Radiology, University Hospitals Dorset, Castle Lane East, Bournemouth, BH7 7DW, UK.
Romaric LoffroyDepartment of Vascular and Interventional Radiology, François-Mitterrand University Hospital, Dijon, France.
Clare BentDepartment of Interventional Radiology, University Hospitals Dorset, Castle Lane East, Bournemouth, BH7 7DW, UK. clare.bent@uhd.nhs.uk.ORCID http://orcid.org/0000-0001-5190-2694

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo describe and test a scoring system for grading embolic penetration in prostate artery embolization (PAE). MATERIALS AND

methodsMulticenter retrospective study of 62 patients undergoing glue-PAE (n-butyl cyanoacrylate methacryloxysulfolane and ethiodized oil). Baseline angiograms and post-embolization radiographs were assessed by four consultant interventional radiologists on two occasions 6 weeks apart, grading depth and density of embolic, according to the described Glue Penetration Index Score (GPIS) and extended GPIS (eGPIS). GPIS (0-3) and eGPIS (0-3.5) scores of each hemigland were summed and whole-gland scores reported. Inter- and intra-observer variability were quantified. Clinical outcomes were assessed at 3 months.

resultsMean reduction in IPSS was 12.9 ± 8.2. Mean whole-gland GPIS was 4.1 ± 1.0 (16.1% ≤ 3; 83.9% > 3). Inter-observer agreement was moderate for GPIS (Fleiss' κ = 0.50, p < 0.0001) and fair for eGPIS (κ = 0.37, p < 0.0001). GPIS scores showed no significant intra-observer variability on repeat scoring (Cochran's Q, p = 0.39), whereas eGPIS did (p = 0.02). Only baseline IPSS correlated with 3-month clinical outcomes.

conclusionGPIS is a repeatable and reproducible score which may assist standardization of the description of extent of glue penetration during PAE in future studies.

Indexed as

Embolization, TherapeuticEnbucrilateEthiodized OilProstateProstatic HyperplasiaAgedAged, 80 and overHumansMaleMiddle AgedRetrospective StudiesTissue AdhesivesTreatment OutcomeEnbucrilateEthiodized OilTissue AdhesivesBenign prostatic enlargementBenign prostatic hypertrophyGlueLipiodolProstate artery embolization

Identifiers

PMID40813473

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.