Evidence map›Paper›PMID 40813463›Full record

ArticleCell death and differentiation2026

ICAM-1 identifies preadipocytes and restricts white adipogenesis by adhering immune cells.

Chunxing Zheng, Jiayin Ye, Qian Yang, Keli Liu, Cheng Chen, Jianchang Cao, Qing Li, Yueqing Xue, Hui Ma, Arnold B Rabson and 6 more

Abstract read
In one paragraph

Article in Cell death and differentiation, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Chunxing Zheng *The Fourth Affiliated Hospital of Soochow University and Institutes for Translational Medicine, Soochow University, Suzhou, China.ORCID 0000-0002-8668-0873
Jiayin Ye *Shanghai Institute of Nutrition and Health, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai, China.ORCID 0000-0002-4695-8287
Qian Yang *Shanghai Institute of Nutrition and Health, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai, China.
Keli Liu *Shanghai Institute of Nutrition and Health, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai, China.ORCID 0000-0001-8008-2162
Cheng ChenDepartment of Plastic Surgery, Zhongshan Hospital, Fudan University, Shanghai, China.
Jianchang CaoShanghai Institute of Nutrition and Health, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai, China.
Qing LiShanghai Institute of Nutrition and Health, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai, China.ORCID 0000-0003-1990-5857
Yueqing XueShanghai Institute of Nutrition and Health, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai, China.
Hui MaThe Third Affiliated Hospital of Soochow University, Changzhou, and Institutes for Translational Medicine, Soochow University, Suzhou, China.
Arnold B RabsonThe Child Health Institute of New Jersey, Rutgers-Robert Wood Johnson Medical School, New Brunswick, NJ, USA.ORCID 0000-0001-5651-2521
Changshun ShaoThe Third Affiliated Hospital of Soochow University, Changzhou, and Institutes for Translational Medicine, Soochow University, Suzhou, China.ORCID 0000-0003-2618-9342
Fei HuaThe Third Affiliated Hospital of Soochow University, Changzhou, and Institutes for Translational Medicine, Soochow University, Suzhou, China.
Lydia SorokinInstitute of Physiological Chemistry and Pathobiochemistry and the Cells-in-Motion Interfaculty Centre (CIMIC), University of Muenster, Muenster, Germany.ORCID 0000-0001-7704-7921
Gerry MelinoDepartment of Experimental Medicine, TOR, University of Rome Tor Vergata, 00133, Rome, Italy.ORCID 0000-0001-9428-5972
Yufang ShiThe Fourth Affiliated Hospital of Soochow University and Institutes for Translational Medicine, Soochow University, Suzhou, China. yfshi@suda.edu.cn.ORCID 0000-0001-8964-319X
Ying WangShanghai Institute of Nutrition and Health, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai, China. yingwang@sibs.ac.cn.ORCID 0000-0002-2571-9367

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Adipose stem cell hierarchy was delineated by scRNA-seq analysis, revealing that ICAM-1, a glycoprotein that mediates cell-cell interaction, is a preadipocyte marker. However, the cellular and molecular mechanisms of how ICAM-1

Indexed as

AdipocytesAdipogenesisAdipose Tissue, WhiteIntercellular Adhesion Molecule-1AnimalsCell AdhesionCell DifferentiationHumansMiceMice, Inbred C57BLObesityIntercellular Adhesion Molecule-1

Identifiers

PMID40813463
PMCPMC12881632

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.