Evidence map›Paper›PMID 40813245›Full record

ArticleGlobal health, science and practice2025

Development of a Cervical Cancer Screening Program in Rural Guatemala.

Taryn McGinn Valley, Elizabeth White, Alli Foreman, Alejandro Chavez, Tana Chongsuwat, Linda Foxworthy, Madhuri Reddy, Cecilia Arroyave, Kevin Wyne, Rafael Tun and 4 more

Abstract read
In one paragraph

Article in Global health, science and practice, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Taryn McGinn ValleyUniversity of Wisconsin-Madison, Madison, WI, USA. tmvalley@wisc.edu.
Elizabeth WhiteUniversity of Wisconsin-Madison, Madison, WI, USA.
Alli ForemanUniversity of California-San Diego, San Diego, CA, USA.
Alejandro ChavezUniversity of California-San Francisco, San Francisco, CA, USA.
Tana ChongsuwatUniversity of Wisconsin-Madison, Madison, WI, USA.
Linda FoxworthyCharles River Community Health, Brighton, MA, USA.
Madhuri ReddyUniversity of Kansas, Kansas City, KS, USA.
Cecilia ArroyaveLiga Contra el Cáncer, Bogotá, Colombia.
Kevin WyneUniversity of Wisconsin-Madison, Madison, WI, USA.
Rafael TunHospital Obras Sociales Monseñor Gregorio Schaffer, San Lucas Tolimán, Sololá, Guatemala.
Yoselin Emelina Letona LópezHospital Obras Sociales Monseñor Gregorio Schaffer, San Lucas Tolimán, Sololá, Guatemala.
Dominga Pic SalazarHospital Obras Sociales Monseñor Gregorio Schaffer, San Lucas Tolimán, Sololá, Guatemala.
Cesia Castro ChutáHospital Obras Sociales Monseñor Gregorio Schaffer, San Lucas Tolimán, Sololá, Guatemala.
Sean DuffyUniversity of Wisconsin-Madison, Madison, WI, USA.

Funding

Integrated Training For Physician-ScientistsT32GM140935 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI Anna Huttenlocher, Jeniel E Nett · 2021 to 2026
$6.5M
NIGMS NIH HHS T32 GM140935
6 · The paper itself

Abstract

backgroundIn San Lucas Tolimán (SLT), Guatemala, a rural municipality with a large Indigenous population, women seeking cervical cancer screening face many barriers. We describe the process from design to implementation of a culturally appropriate and accessible cervical cancer screening and treatment pilot program for women aged 30-49 years.

methodsAfter conducting a community needs assessment, we trained community health workers (CHWs) on basic cervical cancer pathophysiology and human papillomavirus (HPV) self-swab kit use. CHWs provided educational seminars and enrolled interested, eligible women in a mobile health application. Women collected samples at home and returned completed kits to CHWs, who sent the kits to a partner lab. Women who were positive for HPV received follow-up care at the local hospital, where physicians had received training in visual inspection with acetic acid (VIA) with same-day cryotherapy or thermocoagulation. Women with advanced lesions received access to care from gynecologists free of cost.

resultsBetween February and November 2023, of the 230 women eligible to participate in the program, 132 completed HPV self-swabs and received results, and 34 received positive HPV tests (25.76% prevalence). Sixty-seven women had VIA exams as their first screening. Women who received VIA exams had an overall positivity rate of 24.47% (23/94). Twenty-three women received treatment: cryotherapy (n=8), thermocoagulation (n=7), or loop electrosurgical excision procedure (n=8). SLT had higher HPV-positivity rates than nearby Escuintla (21.6%;

conclusionOur screening program found significantly higher HPV-positivity rates in SLT than in previous Guatemalan studies. Our research reinforces that adequately treating cervical cancer in Guatemala requires accompaniment during care and economic support to make care affordable or free. Based on our pilot program, organizations worldwide can further invest in culturally sensitive cervical cancer screening and treatment.

Indexed as

Early Detection of CancerMass ScreeningPapillomavirus InfectionsRural PopulationUterine Cervical NeoplasmsAdultCommunity Health WorkersFemaleGuatemalaHumansMiddle AgedPilot Projects

Identifiers

PMID40813245
PMCPMC12352939

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.