Evidence map›Paper›PMID 40813230›Full record

ReviewRespirology (Carlton, Vic.)2025

Lessons Learned From International Lung Cancer Screening Trials; People at Risk Deserve Screening for Early Detection.

Emily Stone, Henry Marshall, Pan-Chyr Yang, Kwun M Fong

Abstract readReview
In one paragraph

Review in Respirology (Carlton, Vic.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Emily StoneDepartment of Thoracic Medicine and Lung Transplantation, St Vincent's Hospital Sydney; and Melbourne School of Population and Global Health, University of Melbourne, Victoria, Australia; and School of Clinical Medicine UNSW Sydney, Sydney, NSW, Australia.ORCID 0000-0001-9021-8449
Henry MarshallPrince Charles Hospital, Chermside, QLD, Australia; and The University of Queensland Thoracic Research Centre, The Prince Charles Hospital, Brisbane, QLD, Australia.ORCID 0000-0002-9626-8014
Pan-Chyr YangDepartment of Internal Medicine, National Taiwan University College of Medicine; and Institute of Biomedical Sciences, Academia Sinica; and Genomics Research Centre, Academia Sinica, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan.
Kwun M FongPrince Charles Hospital, Chermside, QLD, Australia; and The University of Queensland Thoracic Research Centre, The Prince Charles Hospital, Brisbane, QLD, Australia.ORCID 0000-0002-6507-1403

Funding

Common GoodMedical Research Future FundNational Health and Medical Research Council
6 · The paper itself

Abstract

In the modern era, the role of lung cancer screening by low dose computed tomography (CT) is now broadly accepted, with many jurisdictions offering or intending to offer population-based screening based on high quality randomised controlled trial (RCT) evidence. Optimal implementation will be crucial to ensure sufficiently high participation rates in efficient quality assured lung cancer screening programmes (LCSPs) to achieve the gains predicted by modelling and health technology assessments. Performed well, LCSPs can be anticipated to complement the reduction in lung cancer burden already realised from the introduction of molecularly targeted agents and immune checkpoint inhibitors for advanced stage lung cancer. In this review, we will describe the recent clinical developments from published trials to highlight contemporaneous lung cancer screening (LCS) issues and discuss potential enablers and barriers to the effective implementation of LCSP commonly encountered across the world, particularly from the viewpoint of the Asia Pacific region and peoples.

Indexed as

Early Detection of CancerLung NeoplasmsMass ScreeningHumansRandomized Controlled Trials as TopicTomography, X-Ray ComputedCTlung cancerscreening

Identifiers

PMID40813230
PMCPMC12438035

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.