Evidence map›Paper›PMID 40812822›Full record

Observational studyBMJ open2025

Prenatal particulate matter exposure and risk of bronchopulmonary dysplasia in very preterm infants: a retrospective cohort study.

Wen He, Baihe Feng, Qinglin He, Renjie Chen, Qing Wang, Libo Wang, Yun Cao, Lan Zhang, Jianguo Zhou, Yuanyuan Qi and 5 more

Abstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in BMJ open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Wen He *Department of Respiratory, Children's Hospital of Fudan University, National Children's Medical Center, Shanghai, China.
Baihe Feng *School of Information Engineering, Shanghai Maritime University, Shanghai, China.
Qinglin He *Fudan University School of Public Health, Shanghai, China.
Renjie ChenFudan University School of Public Health, Shanghai, China.
Qing WangDepartment of Respiratory, Children's Hospital of Fudan University, National Children's Medical Center, Shanghai, China.
Libo WangDepartment of Respiratory, Children's Hospital of Fudan University, National Children's Medical Center, Shanghai, China.
Yun CaoDepartment of Neonatology, Children's Hospital of Fudan University, National Children's Medical Center, Shanghai, China.
Lan ZhangDepartment of Neonatology, Children's Hospital of Fudan University, National Children's Medical Center, Shanghai, China.
Jianguo ZhouDepartment of Neonatology, Children's Hospital of Fudan University, National Children's Medical Center, Shanghai, China.
Yuanyuan QiDepartment of Respiratory, Children's Hospital of Fudan University, National Children's Medical Center, Shanghai, China.
Jiayu WangNHC Key Laboratory of Neonatal Diseases, Children's Hospital of Fudan University, National Children's Medical Center, Shanghai, China.
Yingwen WangDepartment of Nursing, Children's Hospital of Fudan University, Shanghai, China.
Jiayu GuoShanghai Key Laboratory of Intelligent Information Processing, Fudan University School of Computer Science, Shanghai, China.
Lin Yuan *Department of Neonatology, Children's Hospital of Fudan University, National Children's Medical Center, Shanghai, China zhangxiaobo0307@163.com drlynnyuan@fudan.edu.cn.
Xiaobo Zhang *Department of Respiratory, Children's Hospital of Fudan University, National Children's Medical Center, Shanghai, China zhangxiaobo0307@163.com drlynnyuan@fudan.edu.cn.ORCID http://orcid.org/0000-0002-0155-5046

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo investigate the associations between maternal fine particulate matter (PM

designRetrospective observational cohort study.

settingA tertiary neonatal intensive care unit in China, 2016-2022.

participants2223 VPIs hospitalised during the study were enrolled after excluding infants with severe congenital malformations, those who abandoned treatment and those who died before discharge. Of these, 59.8% were male. PRIMARY AND SECONDARY OUTCOME MEASURES: We evaluated the effect of maternal PM

resultsAmong 2223 VPIs included in this study, 684 (30.8%) were diagnosed with BPD. Strong correlations were observed between PM exposure and BPD, with each IQR increase during the entire gestational period associated with ORs of 1.254 (95% CI 1.062 to 1.484) for PM

conclusionsMaternal PM exposure, particularly during the second trimester, is significantly associated with BPD in VPIs, with heightened vulnerability in males and infants with lower GA and BW. These findings underscore the need for prenatal air quality interventions and targeted monitoring of high-risk subgroups. Future research should explore PM-induced mechanisms of fetal lung injury and validate these associations in multicentre cohorts.

Indexed as

Air PollutantsBronchopulmonary DysplasiaInfant, Extremely PrematureMaternal ExposureParticulate MatterPrenatal Exposure Delayed EffectsAdultChinaFemaleGestational AgeHumansIncidenceInfant, NewbornMalePregnancyRetrospective StudiesAir PollutantsParticulate MatterNEONATOLOGYPUBLIC HEALTHPulmonary Disease

Identifiers

PMID40812822
PMCPMC12352170

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.