Evidence map›Paper›PMID 40811789›Full record

ArticleBlood advances2025

A patient-derived CABIN1 mutation recapitulates features of idiopathic multicentric Castleman disease in a mouse model.

Dorottya Laczko, Patricia Tsao, Ruth-Anne Pai, Joseph Zinski, Michael V Gonzalez, Melanie D Mumau, Tobias Raabe, Hiromi Muramatsu, Norbert Pardi, Taku Kambayashi and 1 more

Abstract read
In one paragraph

Article in Blood advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Dorottya LaczkoDepartment of Pathology and Laboratory Medicine, University of Pennsylvania, Perelman School of Medicine, Philadelphia, PA.
Patricia TsaoCenter for Cytokine Storm Treatment & Laboratory, University of Pennsylvania, Perelman School of Medicine, Philadelphia, PA.
Ruth-Anne PaiCenter for Cytokine Storm Treatment & Laboratory, University of Pennsylvania, Perelman School of Medicine, Philadelphia, PA.ORCID 0000-0001-9413-7611
Joseph ZinskiCenter for Cytokine Storm Treatment & Laboratory, University of Pennsylvania, Perelman School of Medicine, Philadelphia, PA.ORCID 0000-0002-5120-5386
Michael V GonzalezCenter for Cytokine Storm Treatment & Laboratory, University of Pennsylvania, Perelman School of Medicine, Philadelphia, PA.
Melanie D MumauCenter for Cytokine Storm Treatment & Laboratory, University of Pennsylvania, Perelman School of Medicine, Philadelphia, PA.ORCID 0000-0003-2145-8347
Tobias RaabeDivision of Translational Medicine and Human Genetics, University of Pennsylvania, Perelman School of Medicine, Philadelphia, PA.ORCID 0000-0001-8944-3278
Hiromi MuramatsuDepartment of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA.ORCID 0000-0003-1544-1493
Norbert PardiDepartment of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA.
Taku KambayashiDepartment of Pathology and Laboratory Medicine, University of Pennsylvania, Perelman School of Medicine, Philadelphia, PA.
David C FajgenbaumCenter for Cytokine Storm Treatment & Laboratory, University of Pennsylvania, Perelman School of Medicine, Philadelphia, PA.ORCID 0000-0002-7367-8184

Funding

mTOR as a Central Regulator of iMCD Pathogenesis and Novel Therapeutic TargetR01HL141408 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI Taku Kambayashi · 2018 to 2026
$6.1M
NHLBI NIH HHS R01 HL141408
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID40811789
PMCPMC12767808

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.