ArticlePLoS computational biology2025
A software ecosystem for brain tractometry processing, analysis, and insight.
Article in PLoS computational biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed.
- Anatomy of the Visual Word Form Area in Dyslexia.bioRxiv : the preprint server for biology · 2026Article
- Neonatal brain-age models in full- and preterm infants.Developmental cognitive neuroscience · 2026Article
- Graph-Based White Matter Tractometry: Methods, Applications, and the Path to Validation.Neuroinformatics · 2026Review
- Cortical and white matter myelination proceed in concert during early infancy.Nature communications · 2026Article
- Disrupted integration-segregation balance in the intact hemisphere in chronic spatial neglect.Brain structure & function · 2026Article
- SPECTRA: Spatial Inference for Tractometry Toward Precision Mapping of White Matter Microstructure.bioRxiv : the preprint server for biology · 2026Article
- Neonatal brain-age models in full- and preterm infants.bioRxiv : the preprint server for biology · 2026Article
- What needs to be standardized for reliable, reproducible, and robust tractography?GigaScience · 2026Review
- Free water elimination tractometry for aging brains.Imaging neuroscience (Cambridge, Mass.) · 2025Article
- Massively parallelized brain tractography using compute clusters, supercomputers, and graphics processing units.Imaging neuroscience (Cambridge, Mass.)Article
- Accelerated maturation of brain circuits and executive function in adolescents who experienced the COVID-19 pandemic.Imaging neuroscience (Cambridge, Mass.)Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
16 authors.
Funding
Abstract
Tractometry uses diffusion-weighted magnetic resonance imaging (dMRI) to assess physical properties of brain connections. Here, we present an integrative ecosystem of software that performs all steps of tractometry: post-processing of dMRI data, delineation of major white matter pathways, and modeling of the tissue properties within them. This ecosystem also provides a set of interoperable and extensible tools for visualization and interpretation of the results that extract insights from these measurements. These include novel machine learning and statistical analysis methods adapted to the characteristic structure of tract-based data. We benchmark the performance of these statistical analysis methods in different datasets and analysis tasks, including hypothesis testing on group differences and predictive analysis of subject age. We also demonstrate that computational advances implemented in the software offer orders of magnitude of acceleration. Taken together, these open-source software tools-freely available at https://tractometry.org-provide a transformative environment for the analysis of dMRI data.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.