Evidence map›Paper›PMID 40811709›Full record

ArticlePloS one2025

Musa Paradisiaca derived intrinsically heteroatom doped carbon dots as antioxidant and controlled drug release behavior.

Samiah A Alhabardi, Jawza A Almutairi, Gadah A Al-Hamoud, Zainab Zaki Zakaraya, Umme Hani, Zahrah Ali Ahmed Asiri, Islam Al Freahat, Walaa Alsafadi, Wael Abu Dayyih, Sharuk L Khan and 1 more

Abstract read
In one paragraph

Article in PloS one, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Samiah A AlhabardiDepartment of Pharmaceutics, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia.
Jawza A AlmutairiDepartment of Pharmaceutical Science, College of Pharmacy, Princess Nourah Bint Abdulrahman University, Riyadh, Saudi Arabia.
Gadah A Al-HamoudDepartment of Pharmacognosy, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia.
Zainab Zaki ZakarayaFaculty of Pharmacy, Al-Ahliyya Amman University, Amman, Jordan.
Umme HaniDepartment of Pharmaceutics, College of Pharmacy, King Khalid University (KKU), Abha, Saudi Arabia.
Zahrah Ali Ahmed AsiriDepartment of Pharmaceutics, College of Pharmacy, King Khalid University (KKU), Abha, Saudi Arabia.
Islam Al FreahatDepartment of Biopharmaceutics & Clinical Pharmacy, Faculty of Pharmacy, Al-Ahliyya Amman University, Amman, Jordan.
Walaa AlsafadiDepartment of Pharmaceutics and Pharmaceutical Technology, Faculty of Pharmacy, Alahliyya Amman University, Amman, Jordan.
Wael Abu DayyihFaculty of Pharmacy, Mutah University, Al-Karak, Jordan.
Sharuk L KhanDepartment of Pharmaceutical Chemistry, N.B.S Institute of Pharmacy, Ausa, Latur, Maharashtra, India.
Md Zamshed Alam BeghDepartment of Pharmacy, Faculty of Allied Health Sciences, Daffodil International University, Dhaka, Bangladesh.ORCID https://orcid.org/0009-0002-6512-3872

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This work presents a green, single-step hydrothermal synthesis of intrinsically nitrogen-doped Carbon dots (MCDs) derived from Musa paradisiaca, a low-cost and renewable biomass source. The eco-friendly synthesis avoids external dopants or harsh chemicals, offering a scalable and sustainable alternative to conventional multistep methods. The resulting MCDs, with an average particle size of 4.2 nm (TEM), display desirable surface functionalities (FTIR, XPS) and heteroatom doping. Optical characterization revealed a broad UV-vis absorption at 280 nm and strong blue photoluminescence at 440 nm. DLS and zeta potential measurements confirmed excellent colloidal stability. The MCDs demonstrated high antioxidant activity (>80% radical scavenging) and biocompatibility in cellular assays. Moreover, they enabled controlled drug release, underlining their promise as multifunctional nanocarriers. Given their green synthesis, stability, and performance, these MCDs are highly suitable for future biomedical and clinical applications, particularly in antioxidant therapy and targeted drug delivery.

Indexed as

AntioxidantsCarbonMusaQuantum DotsDelayed-Action PreparationsDrug CarriersDrug LiberationHumansNitrogenParticle SizeAntioxidantsCarbonDelayed-Action PreparationsDrug CarriersNitrogen

Identifiers

PMID40811709
PMCPMC12352835

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.