Evidence map›Paper›PMID 40811552›Full record

ArticleScience (New York, N.Y.)2025

Enantioconvergent benzylic C(sp

Xuzhong Shen, Xiahe Chen, Yihang Xiao, Jesse B Brown, James G Zhang, Xinyuan Ji, Jinyan Rui, Marc Garcia-Borràs, Yi Rao, Yunfang Yang and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Science (New York, N.Y.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Reprogramming NAD(P)Angewandte Chemie (International ed. in English) · 2026
    Article
  3. Article
  4. Biocatalytic Radical C(spResearch square · 2026
    Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Xuzhong ShenDepartment of Chemistry, Johns Hopkins University, Baltimore, MD, USA.ORCID 0000-0002-4779-3584
Xiahe ChenCollege of Chemical Engineering, Zhejiang University of Technology, Hangzhou, Zhejiang, China.
Yihang XiaoDepartment of Chemistry, Johns Hopkins University, Baltimore, MD, USA.
Jesse B BrownDepartment of Chemistry and Biochemistry, Utah State University, Logan, UT, USA.ORCID 0009-0001-9167-5462
James G ZhangDepartment of Chemistry, Johns Hopkins University, Baltimore, MD, USA.ORCID 0000-0002-6802-7061
Xinyuan JiDepartment of Chemistry, Johns Hopkins University, Baltimore, MD, USA.
Jinyan RuiDepartment of Chemistry, Johns Hopkins University, Baltimore, MD, USA.ORCID 0000-0002-8001-4458
Marc Garcia-BorràsInstitut de Química Computacional i Catàlisi (IQCC), Universitat de Girona, Catalonia, Spain.ORCID 0000-0001-9458-1114
Yi RaoDepartment of Chemistry and Biochemistry, Utah State University, Logan, UT, USA.ORCID 0000-0001-9882-1314
Yunfang YangCollege of Chemical Engineering, Zhejiang University of Technology, Hangzhou, Zhejiang, China.ORCID 0000-0002-6287-1640
Xiongyi HuangDepartment of Chemistry, Johns Hopkins University, Baltimore, MD, USA.ORCID 0000-0001-7156-8881

Funding

A Chemo-Mimetic Platform to Reprogram Metalloenzymes for Non-Natural Biocatalytic C-H Functionalization ReactionsR35GM147639 · NIGMS · JOHNS HOPKINS UNIVERSITY · PI Xiongyi Huang · 2022 to 2026
$2.1M
NIGMS NIH HHS R35 GM147639
6 · The paper itself

Abstract

Copper-catalyzed radical C(sp

Indexed as

CopperNonheme Iron ProteinsPhenylalanine HydroxylaseAminationBiocatalysisCatalysisCatalytic DomainDecarboxylationDirected Molecular EvolutionOxidation-ReductionPhthalimidesRhodaminesStereoisomerismCopperNonheme Iron ProteinsPhenylalanine HydroxylasePhthalimidesrhodamine BRhodamines

Identifiers

PMID40811552
PMCPMC13186631

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.