ArticlePloS one2025
Superoxide dismutase VPA1514 in Vibrio parahaemolyticus protects against environmental stresses.
Article in PloS one, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Synergistic Antibacterial Mechanism of Ginger and Rosemary Essential Oils Against Shewanella putrefaciens.Current microbiology · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Vibrio parahaemolyticus is a foodborne enteropathogen that has become a global concern since the emergence of the pandemic O3:K6 strain in 1996. Three putative superoxide dismutases (SODs), namely FeSOD (VP2118), MnSOD (VP2860) and CuZnSOD (VPA1514), are found in V. parahaemolyticus. In this study, the VPA1514 mutant and gene complementary strains of V. parahaemolyticus were constructed to investigate the function of VPA1514 against environmental stresses. The growth of the VPA1514 mutant strain in broth medium under sublethal stress of H2O2 was significantly slowed relative to that of the wild-type strain. The survival rate of this VPA1514 mutant strain, when challenged by lethal acetic acid for two hours, was significantly lower than that of the wild-type strain. Moreover, the presence of the complementary VPA1514 gene significantly ameliorated the survival of this V. parahaemolyticus mutant strain. VPA1514 also showed the effect on the survival of a SOD mutant strain of Escherichia coli against acetic acid. In summary, this study demonstrated that VPA1514 protects against exogenous H2O2 and the lethal concentrations of acetic acid in V. parahaemolyticus.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.