Evidence map›Paper›PMID 40811142›Full record

ReviewInterdisciplinary cardiovascular and thoracic surgery2025

Interdisciplinary Periprocedural Management of Patients Undergoing Transapical TMVI with the Tendyne System: A Narrative Review and Institutional Experience.

Cyril D Ferro, Fabien Praz, Nicolas Brugger, David Reineke, Sandra Terbeck, Florian Setzer, Stephan Windecker, Gabor Erdoes

Abstract readReview
In one paragraph

Review in Interdisciplinary cardiovascular and thoracic surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Cyril D FerroDepartment of Cardiology, Inselspital, Bern University Hospital, University of Bern, 3010 Bern, Switzerland.ORCID 0009-0007-2554-2593
Fabien PrazDepartment of Cardiology, Inselspital, Bern University Hospital, University of Bern, 3010 Bern, Switzerland.ORCID 0000-0001-5416-165X
Nicolas BruggerDepartment of Cardiology, Inselspital, Bern University Hospital, University of Bern, 3010 Bern, Switzerland.ORCID 0000-0002-8778-8421
David ReinekeDepartment of Cardiac Surgery, Inselspital, Bern University Hospital, University of Bern, 3010 Bern, Switzerland.
Sandra TerbeckDepartment of Anesthesiology and Pain Medicine, Inselspital, Bern University Hospital, University of Bern, 3010 Bern, Switzerland.
Florian SetzerDepartment of Cardiac Surgery, Inselspital, Bern University Hospital, University of Bern, 3010 Bern, Switzerland.
Stephan WindeckerDepartment of Cardiology, Inselspital, Bern University Hospital, University of Bern, 3010 Bern, Switzerland.ORCID 0000-0003-2653-6762
Gabor ErdoesDepartment of Anesthesiology and Pain Medicine, Inselspital, Bern University Hospital, University of Bern, 3010 Bern, Switzerland.ORCID 0000-0002-6742-1016

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesMitral regurgitation (MR) represents the most common valvular heart disease (VHD) in the Western world. While transcatheter mitral valve repair (M-TEER) is the leading interventional treatment for surgically high-risk patients, transcatheter mitral valve implantation (TMVI) is reserved for selected patients with unsuitable anatomy for M-TEER. This review aims to summarize our institutional experience with transapical TMVI using the Tendyne valve (Abbott Vascular, CA, USA), focusing on interdisciplinary preoperative, intraoperative, and postoperative management strategies.

methodsWe conducted a narrative review of current literature on TMVI with the Tendyne system and integrated it with a comprehensive analysis of our interdisciplinary clinical experience. Data were collected regarding patient selection, imaging protocols, procedural techniques, and postoperative care.

resultsUtilizing the Tendyne valve, TMVI addresses symptomatic moderate-to-severe or severe MR in patients unsuitable for conventional surgery or M-TEER. Successful outcomes require thorough patient selection, including assessment of mitral annular calcification, absence of intracardiac thrombus, low left ventricular outflow tract (LVOT) obstruction risk, and optimal annular sizing. Multimodal imaging, particularly transoesophageal echocardiography and cardiac computed tomography, is essential for procedural planning and execution. TMVI is performed under general anaesthesia with intraoperative transoesophageal guidance and haemodynamic monitoring to minimize complications such as LVOT obstruction, bleeding, and valve malposition. Postoperative management emphasizes haemodynamic stabilization, bleeding control, and surveillance for paravalvular leaks or device dysfunction.

conclusionsTMVI with the Tendyne valve provides a viable and effective treatment for selected patients with symptomatic relevant MR. Optimal outcomes are dependent on meticulous interdisciplinary collaboration, advanced imaging protocols, and comprehensive perioperative management.

Indexed as

Cardiac CatheterizationHeart Valve ProsthesisHeart Valve Prosthesis ImplantationMitral ValveMitral Valve InsufficiencyPatient Care TeamEchocardiography, TransesophagealHumansPatient SelectionPerioperative CareProsthesis DesignRisk FactorsTreatment Outcomemitral regurgitationmitral stenosistranscatheter edge-to-edge repairtranscatheter mitral valve implantationtranscatheter mitral valve replacement

Identifiers

PMID40811142
PMCPMC12597874

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.