Evidence map›Paper›PMID 40810956›Full record

ArticleEJNMMI physics2025

Toward the standardization of radiopharmaceutical therapies: a technical note evaluating a clinical dosimetry workflow for single-time-point

Taehyung Peter Kim, Wendy Siman, Vivek Mishra, Santiago Aguirre, Siju C George

Abstract read
In one paragraph

Article in EJNMMI physics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Taehyung Peter KimDepartment of Radiation Oncology, Miami Cancer Institute, Miami, FL, USA. tpk.kim@gmail.com.ORCID http://orcid.org/0000-0002-1953-8121
Wendy SimanDepartment of Radiology, University of Colorado School of Medicine, Aurora, CO, USA.
Vivek MishraDepartment of Radiation Oncology, Miami Cancer Institute, Miami, FL, USA.
Santiago AguirreDepartment of Radiation Oncology, Miami Cancer Institute, Miami, FL, USA.
Siju C GeorgeDepartment of Radiation Oncology, Miami Cancer Institute, Miami, FL, USA.ORCID http://orcid.org/0009-0004-5381-6377

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe lack of standardized dosimetry workflows in lutetium-177 (

methodsThe dosimetry workflow evaluated in this study predominatly followed that of MIM SurePlan

resultsMean absorbed dose accuracy improved for both the voxel-based VSV and local deposition (LD) methods until 480 equivalent iterations for all target volumes. DC kernel was found viable for creating reference absorbed doses. The calibration CV was 5.18% when phantom and calibration regions were varied. The VSV method demonstrated absorbed doses that were 10 to 150% higher than those calculated with the LD method. The overall variability in absorbed dose reached up to 84% when reconstruction, calibration, dosimetry, and segmentation methods were varied.

conclusionsA single dosimetry workflow has demonstrated markedly large variability in absorbed dose accuracy. By evaluating the accuracy of absorbed dose, our study helped to propose a harmonized MIM SurePlan

Indexed as

DosimetryRadiopharmaceutical therapiesStandardizationTheranosticsTreatment planning

Identifiers

PMID40810956
PMCPMC12354439

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.