SynthesisSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2025
Management of patients with cancer pain: an evaluation of AGREE II-based clinical practice guidelines.
Synthesis in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
objectiveTo systematically evaluate the clinical practice guidelines for cancer pain management published during 2014-2024, analyze the quality characteristics and recommendations of existing guidelines, and provide an evidence-based basis for the development and implementation of standardized clinical practice guidelines for pain management.
methodsA systematic search of PubMed, OVID, Cochrane Library, China National Knowledge, and other databases was performed to include guidelines related to the management of cancer pain patients. The Appraisal of Guidelines for Research and Evaluation Tool (AGREE II) was used to evaluate the quality of the literature that met the inclusion criteria and to determine the guideline recommendation level.
resultsA total of 23 guidelines were included. AGREE II evaluation results demonstrated that the average scores across six domains were as follows: scope and purpose (97.22%), participants involved in guideline development (73.67%), rigor of development (70.32%), clarity (85.51%), applicability (39.22%), and independence of compilation (81.16%). There were 4 grade A recommendations, 19 grade B recommendations, and no grade C guidelines. The guideline recommendations primarily encompassed five core areas: cancer pain diagnosis, management of special populations, principles of pain management, intervention measures, and pharmaceutical services.
conclusionsExisting clinical practice guidelines for cancer pain management are generally of high quality, but there is still much room for improvement in terms of applicability. It is recommended to optimize the development, dissemination, and application of the guidelines, taking into full consideration the individualized characteristics of patients, in order to further improve the quality of clinical practice in cancer pain management.
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