ReviewInternational urogynecology journal2025
Rethinking Urethral Diverticulum: A Narrative Review of Clinical Outcomes and Cancer Associations.
Review in International urogynecology journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Surgical Techniques for Female Urethral Diverticulectomy: A Systematic Review and Educational Video Presentation.International urogynecology journal · 2026Pooled it
- Durable disease control after multimodal therapy and platinum-based chemotherapy rechallenge in advanced clear cell adenocarcinoma of the urethra with lymph node metastases: a case report.Frontiers in urology · 2026Article
- Reply to "Comment on 'Rethinking Urethral Diverticulum: Awareness, MRI, and the Data Gap on Malignancy'".International urogynecology journal · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introduction and hypothesisUrethral diverticulum (UD) is a rare condition characterized by a pouch-like protrusion of the urethral mucosa into surrounding tissues. This review is aimed at synthesizing data on factors influencing surgical outcomes, postoperative complications, and the association between UD and malignancy.
methodsA comprehensive literature search was conducted for studies published between 2014 and 2024. Inclusion criteria encompassed studies reporting patient outcomes post-UD repair, postoperative complications, or cases of UD-associated malignancy. Data were extracted and analyzed qualitatively owing to the heterogeneity of available studies.
resultsThirty-two studies met the inclusion criteria, totaling 1052 patients with a median age range of 35-62 years; 86% of the patients were female. Transvaginal surgical excision has demonstrated success rates of 83% to 97%. Recurrence rates varied, with primary diverticulectomy showing 2% to 22% and urethroplasty 17%. Larger diverticula (> 3 cm) were linked to increased intraoperative blood loss (mean 450 ml vs 200 ml, p < 0.001). Anatomical complexity, such as circumferential diverticula, was associated with higher postoperative urinary tract infection rates (15% vs 7%, p = 0.02) and reduced surgical success (83% vs 97%, p < 0.05). Postoperative stress urinary incontinence occurred in 4% to 21% of patients. Eighteen cases of UD-associated malignancy were identified, predominantly adenocarcinoma (44%), with a mean age at diagnosis of 51.6 years.
conclusionsSurgical outcomes for UD are influenced by factors such as diverticulum size and anatomical complexity. Postoperative complications are significant considerations. Further research with standardized reporting is essential to enhance understanding and management of UD.
Indexed as
Identifiers
40810904What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.