Evidence map›Paper›PMID 40810757›Full record

ArticleJournal of epidemiology and global health2025

Estimated Incidence of Hospitalisations and Deaths Attributable to Respiratory Syncytial Virus Infections in Adults in Norway between 2010 and 2019: A Time-Series Modelling Study.

Maribel Casas, Caihua Liang, Tor Molden, Robin Bruyndonckx, Mikel Esnaola, Somsuvro Basu, Worku Biyadgie Ewnetu, Pimnara Peerawaranun, Solomon Molalign Moges, Bradford D Gessner and 2 more

Abstract read
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Article in Journal of epidemiology and global health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Maribel CasasP95 Clinical and Epidemiology Services, Leuven, Belgium.
Caihua LiangPfizer Inc, 66 Hudson Boulevard East, New York, NY, 10001-2192, USA. caihua.liang@pfizer.com.
Tor MoldenPfizer AS, Oslo, Norway.
Robin BruyndonckxP95 Clinical and Epidemiology Services, Leuven, Belgium.
Mikel EsnaolaP95 Clinical and Epidemiology Services, Leuven, Belgium.
Somsuvro BasuP95 Clinical and Epidemiology Services, Leuven, Belgium.
Worku Biyadgie EwnetuP95 Clinical and Epidemiology Services, Leuven, Belgium.
Pimnara PeerawaranunP95 Clinical and Epidemiology Services, Leuven, Belgium.
Solomon Molalign MogesP95 Clinical and Epidemiology Services, Leuven, Belgium.
Bradford D GessnerPfizer Inc, 66 Hudson Boulevard East, New York, NY, 10001-2192, USA.
Aleksandra Polkowska-KramekP95 Clinical and Epidemiology Services, Leuven, Belgium.
Elizabeth BegierPfizer Inc, Dublin, Ireland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRespiratory syncytial virus (RSV) can lead to serious respiratory illnesses in both children and adults, particularly affecting older individuals and those with chronic health issues. Due to its symptoms resembling other respiratory viruses and irregular RSV standard-of-care testing, RSV cases in adults frequently remain unreported.

methodsWe retrospectively estimated the incidence of hospitalisations and deaths attributable to RSV in adults in Norway using a time-series model-based approach. Data were obtained from the Norwegian Patient Registry and Norwegian Cause of Death Registry to estimate RSV-attributable hospitalisations and deaths, respectively, among adults from 2010 to 2019. A quasi-Poisson time-series regression model was applied to estimate RSV annual (age- and risk-stratifications) hospitalisation incidence rates (IRs) and mortality rates (per 100,000 person-years).

resultsAnnual RSV-attributable hospitalisation IRs for adults aged ≥ 65 years with risk factors were 289-517 for cardiorespiratory, 243-434 for cardiovascular, and 178-318 per 100,000 person-years for respiratory hospitalisations. RSV-attributable hospitalisations represented 1-3% of total cardiorespiratory hospitalisations. Adults aged 18-44 years with risk factors had similar rates as those aged ≥ 65 years without risk factors. RSV-attributable mortality rates for adults aged ≥ 65 years were 19-35 for cardiorespiratory, 11-19 for respiratory, and 10-18 per 100,000 person-years for cardiovascular deaths. RSV-attributable deaths accounted for 1-5% of total cardiorespiratory deaths.

conclusionsRSV significantly contributes to hospitalisations and deaths in adults in Norway, particularly among older adults and younger adults with underlying diseases. The introduction of RSV vaccines can have a substantial public health impact in reducing the burden of RSV-attributable cardiovascular and respiratory events.

Indexed as

HospitalizationRespiratory Syncytial Virus InfectionsAdolescentAdultAgedAged, 80 and overFemaleHumansIncidenceMaleMiddle AgedNorwayRegistriesRetrospective StudiesRisk FactorsYoung AdultAdult disease burdenHospitalisationMortalityNorwayRespiratory syncytial virusTime-series modelling

Identifiers

PMID40810757
PMCPMC12354426

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.