Evidence map›Paper›PMID 40810714›Full record

ArticleThe Journal of allergy and clinical immunology2025

Asthma programs the transcriptional response of human nasal epithelial cells to SARS-CoV-2 Spike-mediated ACE2 engagement.

Avery DeVries, Hiroki Kimura, Naoko Kimura, Allyson Molzahn, Vadim Pivniouk, Julie G Ledford, Mari Numata, Hong-Wei Chu, Donata Vercelli, Monica Kraft

Abstract readLetter
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of allergy and clinical immunology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Avery DeVriesAsthma and Airway Disease Research Center, The University of Arizona College of Medicine, Tucson, Ariz.
Hiroki KimuraDepartment of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY.
Naoko KimuraDepartment of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY.
Allyson MolzahnDepartment of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY.
Vadim PivnioukAsthma and Airway Disease Research Center, The University of Arizona College of Medicine, Tucson, Ariz; Department of Cellular and Molecular Medicine, The University of Arizona College of Medicine, Tucson, Ariz; BIO5 Institute, The University of Arizona College of Medicine, Tucson, Ariz.
Julie G LedfordAsthma and Airway Disease Research Center, The University of Arizona College of Medicine, Tucson, Ariz; Department of Cellular and Molecular Medicine, The University of Arizona College of Medicine, Tucson, Ariz; BIO5 Institute, The University of Arizona College of Medicine, Tucson, Ariz.
Mari NumataDepartment of Medicine, National Jewish Health, Denver, Colo.
Hong-Wei ChuDepartment of Medicine, National Jewish Health, Denver, Colo.
Donata VercelliAsthma and Airway Disease Research Center, The University of Arizona College of Medicine, Tucson, Ariz; Department of Cellular and Molecular Medicine, The University of Arizona College of Medicine, Tucson, Ariz; BIO5 Institute, The University of Arizona College of Medicine, Tucson, Ariz; Arizona Center for the Biology of Complex Diseases, The University of Arizona, Tucson, Ariz.
Monica KraftDepartment of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY. Electronic address: monica.kraft@mssm.edu.

Funding

SOUTHWEST ENVIRONMENTAL HEALTH SCIENCES CENTERP30ES006694 · NIEHS · UNIVERSITY OF ARIZONA · PI George S Watts · 1994 to 2026
$36.7M
Tollip inhibits IL-33 signaling during airway influenza virus infectionU19AI125357 · NIAID · UNIVERSITY OF ARIZONA · PI KRAFT, MONICA, VERCELLI, DONATA · 2016 to 2025
$14.7M
NIAID NIH HHS U19 AI125357NIEHS NIH HHS P30 ES006694
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

epitheliumgene expressionIL-13SARS-CoV-2Spike

Identifiers

PMID40810714
PMCPMC12667229

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.